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Can a Culturally-Tailored therapy reduce anxiety in advanced cancer patients?

NCT ID NCT07225309

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Aug 04, 2026 · Updated 2 times

Summary

This study tests whether a therapy called Meaning-Centered Psychotherapy for Latinos (MCP-L) can help reduce anxiety and depression in 300 Latino patients with advanced cancer. Participants receive either MCP-L or standard cognitive behavioral therapy over about 3 months. The goal is to see if focusing on meaning and cultural values improves emotional well-being and quality of life.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Meaning-Centered Psychotherapy for Latinos (MCP-L), a structured 7-session therapy focusing on meaning and coping with advanced cancer
What this could lead to
If it works, this could offer a culturally tailored therapy to help Latino patients with advanced cancer feel less anxious and depressed.
What could go wrong
This is a behavioral intervention study, so results depend on participant engagement and may not apply to all groups. The therapy may not outperform standard CBT.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 300 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2026

Expected to finish

Apr 2029

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Patient Eligibility Criteria: A patient cannot be considered eligible for this study unless ALL of the following conditions are met. Participant eligibility will be determined by an initial EMR review followed by a self-report screener and suicide risk assessment. Inclusion Criteria: EMR Criteria \- Documentation of Disease * Pathologically confirmed breast, prostate, colorectal, thyroid, cervix, uteri, or lung - solid tumor cancer (either most recent or new diagnosis) * Definition of Disease \[or Measurable Disease\] * Diagnosed with stages III or IV * Prior Treatment * Receiving ambulatory care at INCan Self-Report Criteria * Age ≥ 18 years * Able to read and communicate in Spanish determined by the question: "Can you read and communicate in Spanish? Yes/No" * Professional role of administrators, clinicians (e.g., oncologists), mental health providers, supervised therapists-in-training (e.g., graduate students), or other related provider delivering the MCP-L experimental intervention * Providing care (or services) to Mexican cancer patients at INCan * Has access to internet and an electronic device * Agrees to be audio-recorded Exclusion Criteria: EMR Criteria * Prior Treatment * Received psychological or psychiatric care at INCan in the last 3 months * In the judgment of the treating physician, protocol investigators, and/or study staff, presence of cognitive impairment (e.g., delirium or dementia) sufficient to preclude meaningful informed consent and/or study participation * Diagnosed with a serious psychiatric condition Self-Report Criteria * Received psychological or psychiatric care outside of INCan in the last 3 months * Presence of suicide risk determined by the Columbia-Suicide Severity Rating Scale * Too ill to participate determined by the question: "Do you feel too ill to participate because of communication problems, uncontrollable pain, or other symptoms that prevent you from participating?" Provider Eligibility Criteria: Inclusion Criteria Self-Report Criteria * Age ≥ 18 years * Able to read and communicate in Spanish determined by the question: "Can you read and communicate in Spanish? Yes/No" * Professional role of administrators, clinicians (e.g., oncologists), mental health providers, supervised therapists-in-training (e.g., graduate students), or other related provider delivering the MCP-L experimental intervention * Providing care (or services) to Mexican cancer patients at INCan * Has access to internet and an electronic device * Agrees to be audio-recorded

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    2 sites in 2 countries. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Instituto Nacional de Cancerología (INCan)

    NOT_YET_RECRUITING

    Mexico City, Mexico

  • Memorial Sloan Kettering Cancer Center

    RECRUITING

    New York, New York, 10065, United States

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