BREAST CANCER INVASIVE

This study looks at whether taking the targeted drug pyrotinib continuously or only at certain times works better to keep HER2-positive breast cancer from coming back. About 488 adults who have already had initial treatment will be randomly assigned to one of the two schedules. T…

This study tests a new approach for people with stage 2 or 3 breast cancer. Before standard chemotherapy, participants receive targeted radiation and an immunotherapy drug (pembrolizumab) injected into the tumor. The goal is to see if this combination can improve the chance of el…

This study tests a special scanner that helps surgeons see cancer cells on removed tissue right during breast-conserving surgery. The goal is to lower the number of women who need a second surgery because some cancer was left behind. About 100 women scheduled for lumpectomy will …

This study is gathering images from up to 800 women with suspicious breast findings to see if a new 3D automated ultrasound system (ATUSA) can accurately detect cancer. Participants will have their standard imaging and biopsy results compared with the ATUSA scans. The goal is to …

This study tests whether drinking tart cherry juice can prevent nerve damage (neuropathy) caused by the chemotherapy drug paclitaxel in people with breast or ovarian cancer. About 86 participants will be randomly assigned to take either a high or low dose of the juice during thei…

This study looks at how the immune system responds in people with early-stage triple negative breast cancer who are receiving standard chemotherapy combined with immunotherapy (pembrolizumab). Researchers will measure certain immune markers in the blood and tumor tissue to see if…

This study is for people with high-risk early-stage breast cancer. It tests whether taking a low dose of the drug azacitidine before surgery can increase immune cells inside the tumor. The goal is to see if this approach can make the body's own defenses fight the cancer more effe…

This study is testing a new blood test (called a liquid biopsy) to track breast cancer over time. About 93 women with early or advanced breast cancer will give blood samples at several visits. The goal is to see if counting cancer cells in the blood can give doctors useful inform…

This study is testing whether short educational videos can help Spanish-speaking Latinx patients with breast or prostate cancer better understand radiation therapy and feel more comfortable about joining clinical trials. About 194 participants will watch a video or read a brochur…