BRAIN DISEASES

This study tests two devices, Supernova and Neutron, that doctors use to remove blood clots from large brain arteries in people having a stroke. The goal is to restore blood flow within 24 hours of symptoms starting. About 3,000 participants will be followed for 90 days to see if…

This study looks at how the brain changes and reorganizes after a stroke that causes arm weakness. Researchers will use MRI scans to track brain activity and connections in 30 adults over six months. The goal is to learn why some people recover better than others, which may help …

This study looks at whether a drug called pramlintide, which mimics a natural body chemical (amylin), can cause migraine attacks in people who get migraines without aura. About 21 adults with a history of migraine without aura will receive either pramlintide or a placebo, and res…

This study tests whether a special camera can capture useful color and brightness details from the brain during neurosurgery. The goal is to help surgeons better tell apart healthy and diseased tissue, or spot active brain areas, beyond what the naked eye can see. About 50 adults…

This study will follow 630 people with brain arteriovenous malformations (AVMs) and aneurysms to learn how well current treatments work and what affects outcomes. Researchers will measure treatment success using imaging and track complications over time. The goal is to better und…

This study looks at whether pramlintide, a substance similar to a natural hormone, can cause migraine-like headaches in people who have had persistent headaches for at least a year after a mild traumatic brain injury. About 21 adults aged 18 to 65 will receive either pramlintide …

This study looks at whether a natural brain chemical called adrenomedullin can cause migraine attacks in people who already get migraines. Researchers will give the chemical to 26 adults with migraine without aura, after they have taken a preventive migraine drug (erenumab). The …