BRAIN DISEASES
Clinical trials for BRAIN DISEASES explained in plain language.
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Promising Alzheimer's drug donanemab enters final phase trial
Disease control OngoingThis study tests whether donanemab can slow memory and thinking decline in people with early Alzheimer's disease. About 1,500 participants with mild symptoms and brain amyloid plaques will receive the drug or a placebo for up to 93 weeks. The main goal is to see if donanemab help…
Matched conditions: BRAIN DISEASES
Phase: PHASE3 • Sponsor: Eli Lilly and Company • Aim: Disease control
Last updated May 26, 2026 02:57 UTC
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New dosing strategy aims to make Alzheimer's drug safer
Disease control OngoingThis study tests whether changing the dose schedule of donanemab can lower the risk of a brain swelling side effect called ARIA-E while still clearing amyloid plaques. About 1,175 adults with early symptomatic Alzheimer's will receive different dosing regimens over 91 weeks. The …
Matched conditions: BRAIN DISEASES
Phase: PHASE3 • Sponsor: Eli Lilly and Company • Aim: Disease control
Last updated May 18, 2026 12:07 UTC
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Brain surgery samples stored for science
Knowledge-focused ENROLLING_BY_INVITATIONThis study collects leftover brain tissue from adults and children having brain surgery. The tissue is stored in a bank and used later for approved research on brain diseases. No direct treatment is given; the goal is to help scientists learn more.
Matched conditions: BRAIN DISEASES
Sponsor: Vanderbilt University Medical Center • Aim: Knowledge-focused
Last updated May 26, 2026 02:57 UTC
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300 Patients' scans to fuel future discoveries
Knowledge-focused OngoingThis study gathers medical images (like MRI and CT scans) from 300 adults—some healthy, some with kidney or brain disease—to create a research library. The images and related health data will be stored and shared with other scientists for not-for-profit studies. No new treatments…
Matched conditions: BRAIN DISEASES
Sponsor: Mario Negri Institute for Pharmacological Research • Aim: Knowledge-focused
Last updated May 26, 2026 02:56 UTC