BORDERLINE PERSONALITY DISORDER (BPD)
Clinical trials for BORDERLINE PERSONALITY DISORDER (BPD) explained in plain language.
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Rewriting your past to fix your future: new therapy for borderline personality disorder
Symptom relief Not yet recruitingThis study tests whether adding autobiographical rewriting workshops to standard therapy helps people with borderline personality disorder improve their social and work life. Participants will either rewrite their personal memories or do general writing, alongside cognitive behav…
Matched conditions: BORDERLINE PERSONALITY DISORDER (BPD)
Phase: NA • Sponsor: University Hospital, Montpellier • Aim: Symptom relief
Last updated May 26, 2026 06:23 UTC
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Can ketamine and therapy together stop suicidal thoughts?
Symptom relief Not yet recruitingThis study tests whether combining ketamine infusions with dialectical behavioural therapy (DBT) can quickly reduce suicidal thoughts in people with treatment-resistant depression and borderline personality disorder. About 120 adults will receive either ketamine or a placebo alon…
Matched conditions: BORDERLINE PERSONALITY DISORDER (BPD)
Phase: PHASE2 • Sponsor: Joshua Rosenblat • Aim: Symptom relief
Last updated May 26, 2026 06:17 UTC
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Ketamine infusions show promise for severe BPD in early trial
Symptom relief Not yet recruitingThis pilot study tests whether two low-dose ketamine infusions, given 24 hours apart, can quickly reduce severe borderline personality disorder (BPD) symptoms. 38 adults with severe BPD will receive the infusions alongside their usual care and be followed for 3 months. The main g…
Matched conditions: BORDERLINE PERSONALITY DISORDER (BPD)
Phase: PHASE2 • Sponsor: University Hospital, Toulouse • Aim: Symptom relief
Last updated May 26, 2026 06:15 UTC
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Could a Culturally-Tuned therapy ease emotional pain in developing nations?
Symptom relief Not yet recruitingThis study tests a version of dialectical behavior therapy (DBT) that has been adapted to fit local cultures in low- and middle-income countries. The goal is to help adults with borderline personality disorder better manage emotions, reduce self-harm, and improve depression and a…
Matched conditions: BORDERLINE PERSONALITY DISORDER (BPD)
Phase: NA • Sponsor: Pakistan Association of Cognitive Therapists • Aim: Symptom relief
Last updated May 22, 2026 14:02 UTC
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Writing away trauma: new group therapy aims to ease PTSD in those with BPD
Symptom relief Not yet recruitingThis study will test if a 10-week virtual group writing therapy can reduce PTSD symptoms in adults who also have borderline personality disorder (BPD) or BPD traits. Participants will write about their trauma using specific instructions during weekly 2-hour online sessions. The g…
Matched conditions: BORDERLINE PERSONALITY DISORDER (BPD)
Phase: NA • Sponsor: St. Joseph's Healthcare Hamilton • Aim: Symptom relief
Last updated May 22, 2026 13:53 UTC
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Could a single day of brain zaps and a pill curb suicidal urges in BPD?
Symptom relief Not yet recruitingThis early-stage study tests a new one-day treatment for adults with borderline personality disorder (BPD) who have recent suicidal thoughts. The treatment combines a medication (D-cycloserine) with up to 20 short sessions of transcranial magnetic stimulation (TMS) over a single …
Matched conditions: BORDERLINE PERSONALITY DISORDER (BPD)
Phase: PHASE1, PHASE2 • Sponsor: Mclean Hospital • Aim: Symptom relief
Last updated May 22, 2026 13:52 UTC
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New therapy aims to ease trauma and borderline symptoms
Symptom relief Not yet recruitingThis study compares a new trauma-focused version of mentalization-based treatment (MBT-TF) with standard MBT for adults who have both borderline personality disorder and complex PTSD. The goal is to see if the new therapy is practical and acceptable to patients and clinicians. Ab…
Matched conditions: BORDERLINE PERSONALITY DISORDER (BPD)
Phase: NA • Sponsor: Eva Rüfenacht • Aim: Symptom relief
Last updated Apr 30, 2026 15:49 UTC
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New study links menstrual cycles to emotional struggles in autistic women
Knowledge-focused Not yet recruitingThis study looks at how emotions change throughout the menstrual cycle in autistic women. Researchers will compare them to women with borderline personality disorder, premenstrual dysphoric disorder, and those without any diagnosed condition. The goal is to better understand emot…
Matched conditions: BORDERLINE PERSONALITY DISORDER (BPD)
Phase: NA • Sponsor: University Hospital, Strasbourg, France • Aim: Knowledge-focused
Last updated May 26, 2026 06:26 UTC
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Scientists ask: is BPD really a 'Relationship Addiction'?
Knowledge-focused Not yet recruitingThis study looks at whether Borderline Personality Disorder (BPD) might be better understood as an addiction to relationships, similar to substance use disorders. Researchers will compare 194 people with BPD, bipolar disorder, and healthy volunteers using questionnaires and tests…
Matched conditions: BORDERLINE PERSONALITY DISORDER (BPD)
Phase: NA • Sponsor: University Hospital, Montpellier • Aim: Knowledge-focused
Last updated May 26, 2026 06:25 UTC
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Brain scans reveal why social rejection hurts more for some
Knowledge-focused Not yet recruitingThis study looks at how the brains of people with borderline personality disorder (BPD) react to feeling left out. Using EEG, researchers will measure brain activity while participants play a virtual ball-tossing game designed to trigger feelings of social exclusion. The goal is …
Matched conditions: BORDERLINE PERSONALITY DISORDER (BPD)
Phase: NA • Sponsor: Hôpital le Vinatier • Aim: Knowledge-focused
Last updated May 26, 2026 06:21 UTC