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Could ketamine ease severe BPD? small trial launches

NCT ID NCT07099534

First seen May 12, 2026 · Last updated Jun 23, 2026 · Updated 8 times

Summary

This pilot study will test whether two intravenous ketamine infusions can quickly reduce symptoms in 38 adults with severe borderline personality disorder. Participants receive the infusions 24 hours apart and are followed for three months. The goal is to see if ketamine, combined with standard care, provides short-term relief.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Toulouse Purpan University Hospital, Head of Psychiatry Clinic in the UF3 department

    Toulouse, 31059, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Ketamine (given intravenously)

What this could lead to

If it works, this could point toward a fast-acting treatment option for severe BPD symptoms.

What could go wrong

This is a very small pilot study (38 people) with no placebo group, so results may not be reliable. Ketamine can cause side effects like dissociation or nausea.

Conditions

The condition(s) this trial relates to.

borderline personality disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.