New study links menstrual cycle to emotional struggles in autistic women
NCT ID NCT06871345
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study looks at how emotional regulation varies across the menstrual cycle in autistic women. Researchers will compare them to women with borderline personality disorder, premenstrual dysphoric disorder, and those without any diagnosed condition. The goal is to better understand these emotional changes and pave the way for more tailored support.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this study could point toward better ways to understand and support emotional challenges in autistic women, especially related to their menstrual cycles.
- What could go wrong
- This is an observational study with no treatment being tested. It is small (90 participants) and early-stage, so results may not apply to all autistic women or lead directly to new therapies.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 90 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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May 2026
An estimate. Start dates often move.
- Expected to finish
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Jul 2029
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 45 years
- Sex
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Female participants only
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion criteria: Common Inclusion Criteria for Healthy Patients and Volunteers: * Female aged 18 to 45; * Woman with regular menstrual cycles (variations in duration, measured between the shortest menstrual cycle) and the longest cycle, remain strictly less than 7 days) between 25 and 35 days; * Woman without hormonal contraception (or NON-hormonal copper IUD) or who has stopped contraception for more than 3 months (and does not wish to take it again); * Woman with a smartphone with an internet connection; * Woman able to understand the objectives and risks of the research and to give informed, dated and signed consent; * Woman affiliated to a social protection health insurance scheme, beneficiary or beneficiary. Patient-specific inclusion criteria: * Specific inclusion criteria for female patients * Patient with a diagnosis of Autism Spectrum Disorder without intellectual disability (ASD), according to DSM-5 criteria OR * Patient with a diagnosis of BPD, according to DSM-5 criteria OR * Patient meeting the diagnostic criteria for PMDD with the SCID Exclusion criteria: Non-inclusion criteria common to healthy patients and volunteers: * Taking hormonal treatment or synthetic steroids; * Woman using hormonal contraceptives (pill, patch, hormonal IUD, vaginal ring, implant, intramuscular injection); * Pregnancy or breastfeeding on the declaration of the person for less than 3 months; * Desire to become pregnant within 3 months of inclusion; * Endocrinopathies (in particular clinical signs of hyperandrogenism) or untreated gynaecological pathologies that may influence menstrual cycles and/or ovulation; * Participation in another study that may interfere with the study; * Inability to give the person informed information (person in an emergency or life-threatening situation); * Woman under judicial protection; * Woman under guardianship or curatorship; * Woman hospitalized for a period \> 24 hours Patient-specific non-inclusion criteria: * Patient with a diagnosis of psychotic disorder; * Patient with a diagnosis of severe substance use disorder, i.e., presence of 6 or more symptoms; * Patient with a diagnosis of bipolar disorder type I or II or cyclothymia; * Patient with a diagnosis of co-occurring ASD and BPD; * Patient with an intellectual disability (IQ ≤ 70); * Patient with neurological comorbidity (e.g., acquired brain injury); * Patient on treatment that alters physiological response (heart rhythm, e.g., beta-blockers). Non-inclusion criteria specific to healthy volunteers: \- Woman with a psychiatric, neurodevelopmental, or neurological history;
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
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