BENIGN PROSTATIC HYPERPLASIA

This study looks at whether it is safe for men with an enlarged prostate to stay on their blood thinners while having laser surgery. About 389 men who take blood thinners will be randomly assigned to either continue or stop their medication during the procedure. The goal is to se…

This study tests a device that uses sound waves (histotripsy) to break down extra prostate tissue in men with benign prostatic hyperplasia (BPH). The goal is to see if it is safe. About 80 men aged 50 and older with moderate to severe symptoms will take part. The treatment is non…

This early-stage study compares two versions of an experimental drug (AD-116 and AD-1161) for benign prostatic hyperplasia (enlarged prostate). It involves 44 healthy adult men who receive a single dose of each version under fed conditions to check safety and how the drug moves t…

This study is testing a new device called the Glean Urodynamics System that monitors bladder function both in the clinic and at home. About 101 adults with bladder problems like overactive bladder or incontinence will use the device. The goal is to see if it is safe and works wel…

This study is testing a new laser surgery approach for men with small prostates that still cause bothersome urinary symptoms. The goal is to see if combining two laser techniques reduces the risk of the bladder neck tightening after surgery, which can block urine flow. About 426 …

This study tests a device that uses mild electrical pulses to calm the nerves controlling the bladder. It aims to reduce urgent, frequent urination and improve quality of life in men with overactive bladder, including those with prostate issues or after prostate surgery. About 15…

This study is tracking 500 men who receive the Optilume BPH Catheter System to treat symptoms of an enlarged prostate, like frequent or difficult urination. The goal is to see how well the device improves symptom scores and how safe it is in everyday use. Participants are treated…

This study tests a device called Optilume that is placed through the penis to open up the prostate and improve urine flow. It is for men aged 50 and older with moderate to severe symptoms from an enlarged prostate. The goal is to see if the device safely reduces symptoms like fre…

This study tests whether a modified surgery that preserves ejaculation works as well as the standard surgery for relieving urinary problems caused by an enlarged prostate. About 336 men over 40 with moderate to severe symptoms will be randomly assigned to one of the two procedure…

This study is testing a robotic platform to help surgeons perform a common prostate surgery called HoLEP for men with an enlarged prostate (BPH). The goal is to see if the robot can successfully complete the surgery without needing to switch to standard methods. About 54 men aged…

This study tests whether using a special catheter to deliver local anesthesia directly into the prostate can replace general anesthesia for a water vapor treatment (Rezum) for enlarged prostate. About 24 men with symptomatic benign prostatic hyperplasia will be randomly assigned …

This study looks at whether doing pelvic floor muscle exercises can help men who have had surgery for an enlarged prostate. The exercises aim to improve bladder control, reduce symptoms like urgency and dribbling, and boost quality of life. About 46 men will be randomly assigned …

This study tests whether adding a traditional Chinese medicine called Lingze tablets to the standard drug tamsulosin can better improve sleep and reduce nighttime urination in men who still have these problems after prostate surgery. About 136 men aged 50 and older will be random…

This study is for men with an enlarged prostate who are starting Finasteride. Researchers want to understand why some men don't get better with this common drug. They will use MRI scans and symptom questionnaires to find clues that could predict who will respond. The goal is to h…

This study is a worldwide registry that will collect information from 7500 men undergoing surgery for an enlarged prostate (BPH). The goal is to track how well different surgical treatments work in real life and what complications occur. By gathering this data, doctors hope to be…