Breakthrough surgery may let men keep ejaculation while treating enlarged prostate
NCT ID NCT07629479
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a new surgical technique for men with an enlarged prostate who have not gotten relief from medication. The goal is to improve urination while preserving the ability to ejaculate. Sixty sexually active men will be randomly assigned to either the new ejaculation-preserving surgery or the standard procedure, and their urinary and sexual function will be compared over six months.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Sep 2025
- Expected to finish
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Sep 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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50 years and older
- Sex
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Male participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Male patients with lower urinary tract symptoms secondary to benign prostatic obstruction after failed medical treatment for at least 3 months. * Sexually active patients with a continuous relationship with the same partner. * International Prostate Symptom Score of 8 or greater. * Transrectal ultrasound-estimated prostate size between 40 and 100 cc. * Eligible for bipolar transurethral enucleation of the prostate. * Ability to complete the required sexual and urinary function questionnaires. * Ability to provide written informed consent. Exclusion Criteria: * Preoperative sexual dysfunction. * Preoperative ejaculatory dysfunction. * Diagnosis or suspicion of prostate cancer. * Neurological disorders affecting lower urinary tract or sexual function. * Detrusor hypocontractility. * Catheter-dependent patients. * Patients with bladder stones. * Inability or refusal to provide informed consent.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Department of Urology- Beni-Suef University Hospitals
RECRUITINGBanī Suwayf, Beni Suweif Governorate, Egypt
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Other studies related to the condition(s) this trial covers.
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