Bariatric surgery

This trial tests whether switching from one inhaled anesthetic (sevoflurane) to another (desflurane) near the end of weight-loss surgery helps patients wake up just as quickly as using desflurane throughout. Adults with obesity scheduled for laparoscopic gastric bypass will be ra…

This trial tests whether converting a prior sleeve gastrectomy to a procedure called intestinal transit bipartition can improve stomach emptying, reduce acid reflux, and help with weight control. Forty adults who had sleeve gastrectomy and now have weight regain or reflux will un…

This study compares two blood-thinning injections (tinzaparin and enoxaparin) to prevent dangerous blood clots after weight loss surgery. About 180 adults having laparoscopic sleeve gastrectomy or gastric bypass will be randomly assigned to one of the two drugs for 21 days after …

This study tests whether it is practical and safe to remove the fallopian tubes during planned weight-loss (bariatric) surgery as a way to lower the risk of ovarian cancer. Many ovarian cancers are thought to start in the fallopian tubes, and removing them can reduce risk by abou…

This study tests whether adding 3D reconstruction and virtual reality to standard body image counselling helps patients feel better about their body after weight-loss surgery. 80 adults on the waiting list for bariatric surgery will be split into two groups: one gets traditional …

This study tests two different drugs—dexmedetomidine and low-dose ketamine—given during weight-loss surgery to see which one reduces pain and the need for morphine afterward. Ninety adults having bariatric surgery will be randomly assigned to one of the two drugs or a placebo. Th…

This study tests if giving the asthma drug salbutamol during weight-loss surgery can improve breathing in obese patients. Researchers will measure lung function during surgery and check for breathing problems afterward. The goal is to see if this simple addition can reduce compli…

This study tests whether listening to a guided imagery recording can reduce pain, anxiety, fear, and stress, and improve sleep quality in people recovering from bariatric surgery. Seventy adults will be randomly assigned to either listen to the recording or receive standard care.…

This study tests whether watching a 20-minute virtual reality video of a calming forest can reduce pain, anxiety, fear, and stress, and improve sleep in people having bariatric surgery. Seventy patients will be randomly assigned to either the VR experience or standard care. Resea…

This study looks at how bariatric surgery affects the liver's energy processing in people with obesity and fatty liver disease. Researchers will use safe, non-radioactive tracer infusions and MRI scans before, during, and six months after surgery to measure changes in liver metab…

This study looks at how two common medications, rosuvastatin (a cholesterol drug) and losartan (a blood pressure drug), are absorbed in people who have had weight-loss surgery. Sixty adults scheduled for either Roux-en-Y gastric bypass or sleeve gastrectomy will take a single dos…

This study investigates whether two specific gene variants (ABCG8 and UGT1A1) are linked to gallstone disease that requires gallbladder removal after bariatric surgery. Researchers compare adults who had weight-loss surgery and later needed their gallbladder removed with those wh…

This study follows 40 adults who recently had laparoscopic sleeve gastrectomy for obesity. Over 6 months, researchers will measure changes in blood sugar, cholesterol, gut barrier markers, and digestive symptoms. The goal is to understand how the surgery affects gut health and me…

This study follows 40 people who recently had laparoscopic sleeve gastrectomy to see how their eating behavior, nutrition, and appetite-regulating hormones change over 6 months. Researchers will measure hormones like ghrelin, GLP-1, and PYY, along with dietary intake and eating a…

This study will follow 200 women who are either taking GLP-1 weight loss drugs or undergoing bariatric surgery. Researchers want to see how these treatments change pelvic floor symptoms like incontinence and prolapse. Participants do not need to have any pelvic floor symptoms to …