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Can a cheaper anesthesia combo speed up waking after bariatric surgery?

NCT ID NCT07748247

Disease control Sponsor: Clínica Dávila Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 05, 2026 · Last updated Aug 06, 2026 · Updated 1 time

Summary

This trial tests whether switching from one inhaled anesthetic (sevoflurane) to another (desflurane) near the end of weight-loss surgery helps patients wake up just as quickly as using desflurane throughout. Adults with obesity scheduled for laparoscopic gastric bypass will be randomly assigned to one of the two anesthesia plans. The main goal is to see if the swap is no worse than continuous desflurane in terms of time to breathing tube removal, with additional checks on nausea, recovery scores, and costs.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Desflurane and a sevoflurane-to-desflurane swap, both inhaled anesthetics used during surgery
What this could lead to
If the swap works as well as continuous desflurane, it could offer a cheaper, equally safe way to wake up faster after weight-loss surgery.
What could go wrong
This is a small, single-center trial, and the swap might not prove non-inferior in all patients. Anesthetics carry risks like nausea or breathing issues.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

About 82 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Aug 2026

An estimate. Start dates often move.

Expected to finish

Apr 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 18 years or older. * Scheduled for elective laparoscopic gastric bypass surgery. * Body mass index between 30 and 50 kg/m². * American Society of Anesthesiologists physical status II or III. * Able and willing to provide written informed consent. Exclusion Criteria: * Surgical procedure lasting less than 2 hours. * Body mass index greater than 50 kg/m². * Significant cardiac disease. * Moderate or severe obstructive respiratory disease, including uncontrolled asthma or chronic obstructive pulmonary disease. * Pregnancy or breastfeeding. * Known allergy or contraindication to medications used during the intraoperative period. * Personal or family history of malignant hyperthermia. * Active illicit drug use or substance dependence. * Advanced chronic kidney disease, defined as an estimated glomerular filtration rate below 60 mL/min. * Myasthenia gravis or another neuromuscular junction disorder. * Severe cognitive or psychiatric disorder. * Refusal to participate or withdrawal of informed consent at any time.

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Conditions

The condition(s) this trial relates to.

Obesity obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Bariatric surgery Obesity

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Clínica Dávila

    Santiago, Santiago Metropolitan, 8431657, Chile

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