AORTIC DISSECTION

This study tests whether giving two drugs—ulinastatin and thymosin α1—right after emergency surgery for a torn aorta can lower the risk of severe inflammation and organ failure. About 200 adults will receive the treatment to see if it helps prevent complications like lung, kidney…

This study looks at using a tube-like device placed through blood vessels (endovascular therapy) to treat bulging or tearing of the main artery in the chest and belly. It includes 170 people who are too high-risk for traditional open surgery. The goal is to see if this approach c…

This study tests a special tube called a stent graft to repair damage in the upper part of the main artery from the heart (the ascending aorta). It is for people with bulges (aneurysms), tears (dissections), or other lesions that usually need open-heart surgery. The goal is to se…

This study follows 352 adults who received the Thoraflex Hybrid device, sometimes with an additional stent, to treat aortic aneurysms or dissections in the chest. Researchers will track safety and success over 10 years, including risks like stroke, spinal cord injury, and death. …

This study follows 301 people who received the AMDS stent to repair a severe tear in the aorta, the body's main artery. The stent helps keep the damaged vessel open and promotes healing. Researchers are tracking survival and how well the aorta recovers over time.

This study is a registry that collects information from 200 patients who had a tear in the wall of the aorta (aortic dissection) and were treated with a procedure called STABILISE. The goal is to see how well the procedure works and what complications may occur. The study does no…

This study looks at two different surgical methods for repairing a life-threatening tear in the aorta (the main artery from the heart). It will compare a less invasive approach for high-risk patients with a more extensive surgery for lower-risk patients. The goal is to find which…

This study involves 40 adults undergoing aortic arch surgery to repair aneurysms or dissections. The goal is to test a new bedside system that measures brain chemicals in near real-time to detect early signs of brain injury. If successful, this could help surgeons take quick acti…