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New Stent-Graft procedure offers hope for High-Risk aortic patients

NCT ID NCT00583817

First seen May 21, 2026 · Last updated Jun 23, 2026 · Updated 3 times

Summary

This study is testing a less invasive procedure using stent-grafts to treat various types of aortic disease, including aneurysms and dissections. It involves 170 participants who are considered too high-risk for traditional open surgery. The goal is to see if this endovascular approach can reduce deaths and serious complications like stroke.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02115, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Endovascular stent-graft implantation (device)

What this could lead to

If successful, this could provide a less invasive treatment option for people with aortic disease who are too high-risk for open surgery.

What could go wrong

This is an early-stage, non-randomized study with no control group, so results may not prove effectiveness. Risks include stroke, death, or incomplete repair.

Conditions

The condition(s) this trial relates to.

Aneurysm aneurysm or dilatation of ascending aorta Aneurysm, Ascending Aorta Aortic Aneurysm, Thoracoabdominal Aortic Dissection Dissection, Ascending Aorta thoracic aortic aneurysm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.