ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION
Clinical trials for ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION explained in plain language.
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Knee surgery showdown: which ACL repair technique wins?
Disease control Recruiting nowThis study compares two surgical methods for fixing a torn ACL, the main knee ligament. Forty adults will be randomly assigned to receive either a single-bundle or double-bundle reconstruction, both combined with an extra ligament repair. Researchers will track knee stability, fu…
Matched conditions: ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION
Phase: NA • Sponsor: Chang Gung Memorial Hospital • Aim: Disease control
Last updated May 26, 2026 03:36 UTC
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New bone screw may improve ACL surgery outcomes
Disease control Recruiting nowThis study compares two types of screws used in ACL reconstruction surgery: a human bone screw and a standard biocomposite screw. The goal is to see if the bone screw reduces bone tunnel widening and lowers the chance of re-injury. About 80 people with a first-time ACL tear will …
Matched conditions: ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION
Phase: NA • Sponsor: Alexander Rofner-Moretti • Aim: Disease control
Last updated May 19, 2026 11:48 UTC
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Could your own fat cells help heal a torn ACL?
Disease control Recruiting nowThis study tests whether a single injection of stem cells taken from your own knee fat pad can safely improve healing and knee function after ACL reconstruction surgery. Fifteen adults having ACL surgery will receive the injection during their procedure and be followed for side e…
Matched conditions: ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION
Phase: PHASE1 • Sponsor: The Methodist Hospital Research Institute • Aim: Disease control
Last updated May 18, 2026 12:02 UTC
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ACL tear? new drug may stop arthritis before it starts
Prevention Recruiting nowThis study tests if a drug called tranexamic acid (TXA), which reduces bleeding, can prevent arthritis after an ACL tear. About 50 people aged 18-30 with a recent ACL injury will receive TXA right after injury and during surgery. Researchers will check joint inflammation, cartila…
Matched conditions: ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION
Phase: PHASE2 • Sponsor: Stanford University • Aim: Prevention
Last updated May 26, 2026 02:48 UTC
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Silk or glue? study tests which incision dressing is gentler after ACL surgery
Symptom relief Recruiting nowThis study compares two wound dressings—silk fibroin and a medical glue—used after ACL reconstruction surgery. Researchers want to see which one leads to fewer skin issues like rashes, blisters, or redness. About 100 people aged 14 to 60 having ACL surgery will take part, and the…
Matched conditions: ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION
Phase: NA • Sponsor: NYU Langone Health • Aim: Symptom relief
Last updated May 26, 2026 03:35 UTC
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Oxygen therapy may boost ACL surgery recovery
Symptom relief Recruiting nowThis study tests if hyperbaric oxygen therapy (breathing pure oxygen in a pressurized chamber) can help people recover faster after anterior cruciate ligament (ACL) knee reconstruction. About 40 adults aged 18-45 who need ACL surgery will be randomly assigned to receive HBOT or s…
Matched conditions: ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION
Phase: NA • Sponsor: Assaf-Harofeh Medical Center • Aim: Symptom relief
Last updated May 22, 2026 13:50 UTC
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New device may make ACL surgery less painful
Symptom relief Recruiting nowThis study tests if a new tool called a dual-flow arthroscopy sheath can replace the standard tourniquet during ACL knee surgery. The goal is to see if it reduces pain and complications after surgery. About 128 adults having their first ACL reconstruction will be randomly assigne…
Matched conditions: ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION
Phase: NA • Sponsor: Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer • Aim: Symptom relief
Last updated May 20, 2026 11:56 UTC
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New study aims to find best pain relief for kids after knee surgery
Symptom relief Recruiting nowThis study compares two nerve block methods (AFCN block vs. adductor canal block) for pain control in children aged 8-18 having ACL or MPFL knee surgery. Researchers will measure pain levels, opioid use, and muscle strength recovery. The goal is to find which block provides bette…
Matched conditions: ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION
Phase: PHASE4 • Sponsor: Hospital for Special Surgery, New York • Aim: Symptom relief
Last updated May 18, 2026 12:07 UTC
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ACL rehab gets a boost: blood flow restriction may speed healing
Knowledge-focused Recruiting nowThis study looks at how using a special cuff to limit blood flow during exercise affects immune cells and energy use in people recovering from ACL surgery. Twenty adults aged 18 to 60 will complete two exercise sessions to measure changes in genes, blood sugar, and stress hormone…
Matched conditions: ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION
Phase: NA • Sponsor: Yale University • Aim: Knowledge-focused
Last updated May 26, 2026 03:44 UTC
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Fractal cues may rewire brains of ACL athletes
Knowledge-focused Recruiting nowThis study looks at how a single walking session with different visual cues affects movement and brain signals in 36 athletes who had ACL surgery. One type of cue is steady (isochronous), while the other has natural variations (fractal). The goal is to see if fractal cues can res…
Matched conditions: ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION
Phase: NA • Sponsor: Egas Moniz - Cooperativa de Ensino Superior, CRL • Aim: Knowledge-focused
Last updated May 15, 2026 11:53 UTC