ALOPECIA AREATA

This study looked at the long-term safety and effectiveness of a drug called CTP-543 for adults with moderate to severe alopecia areata, a condition that causes patchy hair loss. Over 400 people who had already completed a previous CTP-543 trial took part. Researchers measured ha…

This study tested the safety and effectiveness of tofacitinib, a drug that blocks certain immune signals, for treating skin conditions like eczema and psoriasis in people with Down syndrome. 47 adolescents and adults took part. The goal was to see if the drug could improve these …

This study tested a daily pill called baricitinib in 606 adults with severe or very severe alopecia areata, a condition causing major hair loss. The goal was to see if it could safely regrow scalp hair compared to a placebo. Results showed that more people taking baricitinib achi…

This study tested baricitinib, a pill, in 784 adults with severe or very severe alopecia areata, a condition causing major hair loss. Participants received either a low or high dose of baricitinib or a placebo to see if it could regrow scalp hair. The goal was to reduce hair loss…

This study tested an oral medication called roflumilast against steroid injections for people with mild to moderate patchy alopecia areata, a condition causing hair loss. Fifty adults took part, and researchers measured how much hair regrew over 16 weeks. The goal was to see if t…

This study tested whether low doses of IL2, a protein that helps regulate the immune system, could treat severe alopecia areata (patchy hair loss). 44 adults with at least 50% scalp hair loss that did not respond to standard treatments received either IL2 or a placebo. The goal w…

This study looked at the long-term safety and effectiveness of an experimental drug (PF-06651600) for adults and teens aged 12 and older with alopecia areata, a condition that causes patchy or total hair loss. Over 1,000 participants received the drug for up to several years, and…

This study tested a portable light device called Lumiton in 18 adults with psoriasis, alopecia areata (hair loss), or polymorphous light eruption (sun allergy). The goal was to see if using the device at home could improve disease severity. Researchers measured changes through ph…

This study explored whether a specific gene variation (TLR7) is linked to alopecia areata, an autoimmune condition that causes patchy hair loss. Researchers compared the gene patterns of 120 people—some with the condition and some without—to see if the gene affects who gets it an…