Small study reveals immune changes after hair loss drug
NCT ID NCT07645430
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at 20 adults with severe alopecia areata (hair loss) to see how the drug baricitinib changes certain immune markers in the blood. Researchers measured levels of two proteins, interleukin-15 and interferon gamma, before and after six months of treatment. The goal was to understand how the drug works, not to test if it cures the condition.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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20 people
The number who actually took part.
- Started
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Jan 2023
- Finished
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Jun 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 50 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults diagnosed clinically with Alopecia Areata. * Severity of alopecia tool (SALT) score greater than 50. * Only patients with disease duration exceeding six months but less than eight years will be included. Exclusion Criteria: * Patients were excluded if they were pregnant or lactating, and had chronic hepatic or renal disease. * Cases diagnosed with malignancy, scalp infections, or other types of alopecia will also excluded from the current study. * Recent use of systemic treatment within the last 3 months or topical treatment within the last 4 weeks also will be excluded.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Faculty of medicine, Benha University (Dermatology department)
Banhā, 13511, Egypt
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Other studies related to the condition(s) this trial covers.
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