ADVANCED SOLID TUMOR CANCER

This early-stage study is testing a new drug called ABBV-CLS-484 in people with advanced solid tumors that have spread or returned after previous treatments. Researchers want to find safe doses when the drug is given alone and when combined with two other cancer medications. The …

This is the first time the experimental drug BNT3214 will be given to people. The study aims to find safe doses and see if it helps adults with advanced solid tumors that have stopped responding to standard treatments. Researchers will test different dose levels in small groups f…

This study is testing an experimental drug called Trastuzumab Rezetecan in people with advanced HER2-positive cancers that have stopped responding to standard treatments. The trial will enroll 90 patients with specific rare or hard-to-treat tumors to see if the drug can shrink th…

This study is testing whether a new drug called LM-24C5, when combined with other cancer treatments, can help control advanced solid tumors that have a specific marker called CEACAM5. It will involve about 130 adults with advanced cancer that has returned or isn't responding to s…

This is an early-stage trial testing a new drug called HC010 when given alongside standard chemotherapy to people with advanced lung cancer. The main goals are to find a safe and tolerable dose and to get a first look at whether the combination might help control the cancer. The …

This early-stage study aims to find a safe and tolerable dose of an investigational drug called HC010 when given alongside standard chemotherapy to people with advanced solid tumors, particularly gastrointestinal cancers. Researchers will closely monitor side effects and how the …

This is an early-stage safety study testing a new treatment called X-PACT for people with advanced solid tumors that have spread or returned. The treatment involves injecting a drug and a special material directly into a tumor, then applying X-ray energy to activate it. The main …