New Triple-Action therapy takes aim at Hard-to-Treat cancers
NCT ID NCT04389281
First seen Jan 05, 2026 · Last updated May 23, 2026 · Updated 26 times
Summary
This early-stage trial is testing a new treatment called X-PACT for people with advanced head and neck cancer, breast cancer, soft tissue sarcoma, or melanoma. The treatment involves injecting a special drug and tiny light-producing particles directly into the tumor, then exposing it to X-rays to activate the drug and kill cancer cells. The main goal is to check if the treatment is safe, and it is open to adults whose cancer has not responded to standard therapies.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Duke University
RECRUITINGDurham, North Carolina, 27710, United States
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Levine Cancer Institute
RECRUITINGCharlotte, North Carolina, 28204, United States
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Prisma Health
RECRUITINGGreenville, South Carolina, 29605, United States
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Sibley Hospital - Johns Hopkins University
RECRUITINGWashington D.C., District of Columbia, 20016, United States
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Conditions
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