X-Ray activated therapy shows promise for Hard-to-Treat cancers
NCT ID NCT04389281
First seen Jan 05, 2026 · Last updated May 16, 2026 · Updated 23 times
Summary
This early-stage trial tests a new treatment called X-PACT for people with advanced head and neck cancer, breast cancer, soft tissue sarcoma, or melanoma that has not responded to standard therapies. The treatment involves injecting a special drug and device directly into the tumor, then activating it with X-rays to kill cancer cells. The main goal is to check if the treatment is safe, and it is open to adults with certain advanced solid tumors.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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Duke University
RECRUITINGDurham, North Carolina, 27710, United States
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Levine Cancer Institute
RECRUITINGCharlotte, North Carolina, 28204, United States
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Prisma Health
RECRUITINGGreenville, South Carolina, 29605, United States
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Sibley Hospital - Johns Hopkins University
RECRUITINGWashington D.C., District of Columbia, 20016, United States
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Conditions
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