Adolescent obesity

This study tests whether weighing yourself every day can help teens with obesity manage their weight. About 99 teens aged 12 to 18 will be split into three groups: usual care, usual care plus a simple scale, or usual care plus a smart scale that sends data to their doctor. The st…

This trial tests whether an essential amino acid supplement can lower fat stored in the liver of teenagers with non-alcoholic fatty liver disease (NAFLD). Participants aged 13 to 18 will take the supplement or a placebo for two months, and researchers will measure liver fat with …

This study looked at 150 teens aged 12-17 with severe obesity to find the best time to add a weight-loss pill (phentermine) if lifestyle changes alone weren't enough. Participants first tried lifestyle therapy for 12 or 24 weeks, then those who didn't lose enough weight started t…

This study tested whether a daily cocoa flavonol supplement could improve body composition, metabolism, and inflammation in 104 obese teenagers aged 10 to 16. Participants took either the supplement or a placebo for 12 weeks, alongside standard diet and exercise advice. The goal …

This study tested a 'digi-physical' approach for families with children or teens living with obesity. Participants either received standard in-person care or a mix of digital tools (an app for tracking health and chatting with caregivers) plus fewer in-person visits. The goal was…

This study looked at whether weight-loss surgery (vertical sleeve gastrectomy) can improve kidney, heart, and pancreas function in teens aged 12-21 with type 2 diabetes and obesity. Researchers measured blood flow to the kidneys, kidney filtering ability, and insulin production b…

This completed study tested whether the diabetes drug semaglutide (Rybelsus) could help 60 adolescent girls with PCOS and obesity reduce liver fat and improve insulin sensitivity, compared to a weight loss diet. Participants took a daily oral tablet for 4 months or followed a pre…

This study looked at whether a type of talk therapy (cognitive-behavioral therapy) could improve how the body uses insulin in teenage girls at risk for type 2 diabetes. The 147 participants were girls aged 12-17 with depressive symptoms and a family history of diabetes. The thera…

This study tested whether group-based telehealth visits could help teens with obesity manage their weight. 66 adolescents participated in 12 virtual sessions over 6 months, covering nutrition, physical activity, and mental health. Researchers compared their results to teens who a…

This study looked at whether a single session of isometric exercise (like squats and planks) or aerobic exercise (like running) is better at lowering blood pressure in teenagers aged 13 to 17.5 who are overweight or obese. 38 teens were randomly assigned to one type of exercise, …

This study follows adolescents with youth-onset type 2 diabetes, along with obese and lean peers, into young adulthood to see how their kidneys change over time. Using advanced imaging and kidney function tests, researchers aim to understand early signs of diabetic kidney disease…

This study looked at 20 teens aged 13-20 with severe obesity who were scheduled for bariatric surgery. Researchers measured liver fat and how the body processes energy before and one year after surgery. The goal was to understand how the surgery affects liver health and metabolis…