Therapy for depression may also protect against diabetes in teens
NCT ID NCT03263351
First seen Nov 01, 2025 · Last updated Jun 23, 2026 · Updated 30 times
Summary
This study looked at whether a type of talk therapy (cognitive-behavioral therapy) could improve how the body uses insulin in teenage girls at risk for type 2 diabetes. The 147 participants were girls aged 12-17 with overweight or obesity, mild to moderate depression, and a family history of diabetes. The therapy group learned to change negative thoughts and increase pleasant activities, while a comparison group received general health education. Researchers measured changes in insulin sensitivity, depression, eating, activity, and sleep over one year.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for DEPRESSION are added.
Genom att skicka in godkänner du våra Användarvillkor
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
Genom att skicka in godkänner du våra Användarvillkor
Locations
-
Children's Hospital Colorado
Aurora, Colorado, 80045, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
cognitive-behavioral therapy (Blues Program)
What this could lead to
If successful, this approach could offer a way to lower type 2 diabetes risk in teenage girls by treating depression.
What could go wrong
This is a completed study with modest size (147 participants) and no phase designation, so results may not apply broadly. The intervention is behavioral, not a drug, so effects may be limited.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.