ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS)
Clinical trials for ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS) explained in plain language.
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Could a common steroid save lives in severe lung failure?
Disease control Not yet recruitingThis study tests whether the steroid dexamethasone, when added to standard care, can lower the chance of death within 90 days for adults with severe lung injury caused by sepsis. About 1,474 patients on breathing machines will receive either dexamethasone or a placebo. The goal i…
Matched conditions: ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS)
Phase: PHASE3 • Sponsor: Southeast University, China • Aim: Disease control
Last updated May 26, 2026 09:59 UTC
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Could a shock drug help ARDS patients breathe easier?
Disease control Not yet recruitingThis study tests whether centhaquine, a drug already approved for shock, can help people with moderate to severe acute respiratory distress syndrome (ARDS), a life-threatening lung condition. About 80 adults in the ICU will receive either centhaquine or a placebo alongside standa…
Matched conditions: ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS)
Phase: PHASE2 • Sponsor: Pharmazz, Inc. • Aim: Disease control
Last updated May 26, 2026 09:58 UTC
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New lung-saving strategy aims to reduce ventilator damage in ARDS
Disease control Not yet recruitingThis study tests a new way to use breathing machines for people with severe lung failure (ARDS). The goal is to use very gentle breaths to avoid further lung damage, while a special life-support machine helps with oxygen and carbon dioxide removal. About 290 adults on breathing m…
Matched conditions: ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS)
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Disease control
Last updated May 26, 2026 09:35 UTC
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Ancient herbal mix takes on modern lung killer in major trial
Disease control Not yet recruitingThis study tests whether a traditional Chinese herbal formula, Xuanbai Shengmai Decoction, can improve survival in adults with acute respiratory distress syndrome (ARDS), a severe lung condition often seen in the ICU. About 308 participants will receive either the herbal decoctio…
Matched conditions: ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS)
Phase: PHASE3 • Sponsor: Southeast University, China • Aim: Disease control
Last updated May 22, 2026 13:54 UTC
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New inhaled treatment aims to get ICU patients off ventilators faster
Disease control Not yet recruitingThis study tests whether an inhaled drug called aprotinin can help adults with moderate to severe acute respiratory distress syndrome (ARDS) recover faster. About 156 critically ill patients in intensive care will receive either aprotinin or a placebo, plus standard care. The mai…
Matched conditions: ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS)
Phase: PHASE3 • Sponsor: Fundacion del Hospital Nacional de Paraplejicos para la Investigacion y la Integracion • Aim: Disease control
Last updated May 18, 2026 12:12 UTC
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ER study to reveal best oxygen strategy for critical breathing failure
Disease control Not yet recruitingThis study looks at 500 adults in the emergency room with dangerously low oxygen levels. It compares two non-invasive breathing supports: a pressurized face mask and high-flow nasal oxygen. The goal is to see which method improves survival, reduces time on a breathing machine, an…
Matched conditions: ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS)
Phase: NA • Sponsor: Ohio State University • Aim: Disease control
Last updated May 13, 2026 16:03 UTC
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Pilot study tests best ventilation strategy for severe breathing trouble
Knowledge-focused Not yet recruitingThis study looks at two ways of using a breathing machine in ICU patients with dangerously low oxygen levels. The goal is to see if it's possible to run a larger trial comparing letting patients breathe on their own versus fully controlling their breathing. About 80 adults will t…
Matched conditions: ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS)
Phase: NA • Sponsor: Oslo University Hospital • Aim: Knowledge-focused
Last updated May 26, 2026 10:00 UTC
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Ventilator settings may impact organ congestion in ARDS
Knowledge-focused Not yet recruitingThis study looks at how different levels of ventilator pressure affect blood flow congestion in the abdomen of patients with acute respiratory distress syndrome (ARDS). Researchers will use ultrasound to grade congestion in the liver, kidneys, and portal vein as absent, moderate,…
Matched conditions: ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS)
Sponsor: University Hospital, Angers • Aim: Knowledge-focused
Last updated May 26, 2026 09:58 UTC
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New study hopes to unlock ARDS secrets through blood and sputum analysis
Knowledge-focused Not yet recruitingThis study will collect blood and sputum samples from 411 adults with acute respiratory distress syndrome (ARDS) who are on a breathing machine. Researchers will analyze the samples to find biological markers that can predict how well patients respond to ventilation and their cha…
Matched conditions: ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS)
Sponsor: Ruijin Hospital • Aim: Knowledge-focused
Last updated May 26, 2026 09:54 UTC
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AI predicts who will survive lung failure after turning therapy
Knowledge-focused Not yet recruitingThis study looks at 377 adults with severe lung failure (ARDS) who received a treatment called prone positioning (lying on the belly to help breathing). Researchers will use computer models to find patterns in patient data that can predict who is at highest risk of dying in the I…
Matched conditions: ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS)
Sponsor: Shanghai Zhongshan Hospital • Aim: Knowledge-focused
Last updated May 22, 2026 14:04 UTC
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800 ARDS patients to be studied for better treatment insights
Knowledge-focused Not yet recruitingThis study will observe 800 adults with acute respiratory distress syndrome (ARDS) in the intensive care unit to learn about their symptoms, treatments, and recovery. Researchers will collect data from medical records and devices, and ask survivors about their quality of life. Th…
Matched conditions: ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS)
Sponsor: Jee Hwan Ahn • Aim: Knowledge-focused
Last updated May 22, 2026 13:55 UTC
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New study aims to close deadly gap in breathing failure care for hispanic patients
Knowledge-focused Not yet recruitingThis study aims to improve care for Hispanic patients with acute respiratory distress syndrome (ARDS), a severe breathing problem. Hispanic patients are twice as likely to die from this condition as non-Hispanic patients. The researchers will work with doctors, nurses, and famili…
Matched conditions: ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS)
Phase: NA • Sponsor: New York University • Aim: Knowledge-focused
Last updated May 22, 2026 13:53 UTC
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New study explores safer positions for ARDS patients to improve lung function
Knowledge-focused Not yet recruitingThis study looks at whether lying on the side at different angles can improve lung function in patients with acute respiratory distress syndrome (ARDS), a serious lung condition. Researchers will use a special imaging tool to monitor how air moves in the lungs during position cha…
Matched conditions: ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS)
Phase: NA • Sponsor: The Fourth Affiliated Hospital of Zhejiang University School of Medicine • Aim: Knowledge-focused
Last updated May 19, 2026 12:01 UTC
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Ventilator settings may impact kidney function in lung patients
Knowledge-focused Not yet recruitingThis study looks at 40 adults with acute respiratory distress syndrome (ARDS) who need a breathing machine. Researchers want to see if changing the pressure in the lungs affects kidney health. They will measure kidney injury and the need for dialysis during the ICU stay.
Matched conditions: ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS)
Sponsor: Fayoum University • Aim: Knowledge-focused
Last updated May 18, 2026 12:13 UTC