ACUTE MYELOID LEUKEMIA (AML)

This study tested whether two drugs, venetoclax and azacitidine, could help people with acute myeloid leukemia (AML) live longer after a stem cell transplant. The trial included adults and teenagers who had a stem cell transplant or were planning one. The goal was to see if this …

This early-phase study tested a new drug called voruciclib, alone or combined with another drug (venetoclax), in adults with certain blood cancers (like lymphoma or leukemia) that had returned or stopped responding to standard treatments. The main goal was to check safety and fin…

This early-stage trial tested a new treatment for acute myeloid leukemia (AML), a blood cancer that had come back or not responded to standard care. The therapy uses a patient's own immune cells, modified to recognize and attack cancer cells carrying a specific marker (CD123). Th…

This early-phase study tested two experimental drugs, VOB560 and MIK665, together in 37 people with relapsed or refractory non-Hodgkin lymphoma, acute myeloid leukemia, or multiple myeloma. The goal was to find safe doses and see if the combination could kill cancer cells by bloc…

This study tested a drug called ADCT-301 in people whose blood cancer (AML, MDS, or related conditions) came back after a stem cell transplant. Only 3 people took part before the study was stopped early. The goal was to see if the drug is safe and can help achieve remission. Risk…

This study tested an experimental drug called NMS-03592088 in 63 adults with acute myeloid leukemia (AML) or chronic myelomonocytic leukemia (CMML) that had come back or not responded to standard treatments. The goal was to find a safe dose and see if the drug could shrink or con…

This study tested a new drug called GEN3014 in people with blood cancers like multiple myeloma, lymphoma, and leukemia that had returned or stopped responding to treatment. The main goal was to check the drug's safety and find the best dose. About 130 people took part, but the st…

This early-stage study tested two new drug combinations (HDM201 with MBG453 or venetoclax) in adults with acute myeloid leukemia (AML) or high-risk myelodysplastic syndrome (MDS). The main goal was to check safety and find the right dose. The study was stopped early, so results a…

This study tested a drug called gilteritinib, which targets a specific genetic change (FLT3/ITD) in acute myeloid leukemia (AML), combined with standard chemotherapy. It included 9 children, teens, and young adults whose leukemia had come back or not responded to treatment. The g…

This study looked at using umbilical cord blood transplants after strong chemotherapy and radiation to treat various blood cancers like leukemia and lymphoma. It included 200 people and aimed to see how many survived one year after the transplant. The approach is intense and mean…