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New combo therapy shows promise for young leukemia patients

NCT ID NCT04240002

First seen Jan 09, 2026 · Last updated May 23, 2026 · Updated 18 times

Summary

This study tested a drug called gilteritinib, which targets a specific genetic change (FLT3/ITD) in acute myeloid leukemia (AML), combined with standard chemotherapy. It included 9 children, teens, and young adults whose leukemia had come back or not responded to treatment. The goal was to find the best dose and see how many patients achieved remission. The study was stopped early, but results help guide future research.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • SIte IT39001

    Roma, 165, Italy

  • Site DE49004

    Essen, North Rhine-Westphalia, 45147, Germany

  • Site ES34001

    Barcelona, 08950, Spain

  • Site GB44001

    Birmingham, B4 6NH, United Kingdom

  • Site GB44005

    Cardiff, CF14 4XW, United Kingdom

  • Site UK44007

    Sutton, United Kingdom

  • St. Jude Children's Research Hospital

    Memphis, Tennessee, 38105, United States

Conditions

Explore the condition pages connected to this study.