ACUTE LYMPHOBLASTIC LEUKEMIA
Clinical trials for ACUTE LYMPHOBLASTIC LEUKEMIA explained in plain language.
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Leukemia drug trial halted early: what we know
Disease control TerminatedThis study tested a drug called calaspargase pegol in adults aged 22 and older with a specific type of acute lymphoblastic leukemia (ALL). The goal was to find the right dose and check for side effects. The trial was stopped early, but the information gathered helps researchers u…
Matched conditions: ACUTE LYMPHOBLASTIC LEUKEMIA
Phase: PHASE2, PHASE3 • Sponsor: Institut de Recherches Internationales Servier • Aim: Disease control
Last updated May 26, 2026 03:23 UTC
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Blood cancer transplant study tests safer drug combo to prevent deadly complication
Disease control TerminatedThis study looked at people with blood cancers receiving a stem cell transplant from an unrelated donor. The goal was to find which of two drug combinations (cyclosporine and sirolimus with either MMF or post-transplant cyclophosphamide) better prevents a serious side effect call…
Matched conditions: ACUTE LYMPHOBLASTIC LEUKEMIA
Phase: PHASE2 • Sponsor: Fred Hutchinson Cancer Center • Aim: Disease control
Last updated May 26, 2026 03:15 UTC
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Targeted drug combo in stem cell transplants shows promise but study halted early
Disease control TerminatedThis study looked at adding the targeted drug inotuzumab ozogamicin to standard chemotherapy before and after a stem cell transplant for people with certain blood cancers like leukemia and lymphoma. The goal was to see if it was safe and could help control the cancer. The study w…
Matched conditions: ACUTE LYMPHOBLASTIC LEUKEMIA
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 26, 2026 03:11 UTC
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Experimental Dual-Target CAR-T therapy shows promise for Tough-to-Treat leukemia
Disease control TerminatedThis early-phase study tested a personalized cell therapy (CAR-T) that targets two proteins, CD19 and CD20, on leukemia cells. It involved 5 patients with B-cell acute lymphoblastic leukemia that had returned or not responded to standard treatments. The main goal was to check saf…
Matched conditions: ACUTE LYMPHOBLASTIC LEUKEMIA
Phase: PHASE1 • Sponsor: Medical College of Wisconsin • Aim: Disease control
Last updated May 26, 2026 03:04 UTC
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New hope for kids with lingering leukemia: targeted drug aims to wipe out hidden cancer cells
Disease control TerminatedThis study tested a drug called inotuzumab ozogamicin (Besponsa) in children and young adults with a type of leukemia (B-ALL) that still had small amounts of cancer cells after standard treatment. The drug works like a smart bomb, targeting a protein (CD22) found on most leukemia…
Matched conditions: ACUTE LYMPHOBLASTIC LEUKEMIA
Phase: PHASE2 • Sponsor: St. Jude Children's Research Hospital • Aim: Disease control
Last updated May 22, 2026 13:50 UTC
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Cancer combo trial for tough leukemia ends early
Disease control TerminatedThis study tested whether adding ponatinib to standard chemotherapy and venetoclax could help people with T-cell acute lymphoblastic leukemia that came back or didn't respond to prior treatment. Only 4 people enrolled before the study was stopped early. The goal was to see how ma…
Matched conditions: ACUTE LYMPHOBLASTIC LEUKEMIA
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 20, 2026 11:57 UTC
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Promising leukemia combo trial for kids ends early
Disease control TerminatedThis study tested a drug called isatuximab added to standard chemotherapy for children aged 28 days to under 18 years whose leukemia (ALL or AML) had returned or stopped responding to treatment. The goal was to see if the combination could help achieve complete remission. The tri…
Matched conditions: ACUTE LYMPHOBLASTIC LEUKEMIA
Phase: PHASE2 • Sponsor: Sanofi • Aim: Disease control
Last updated May 18, 2026 11:59 UTC
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Can vitamins fix liver damage from chemo? small study cut short
Symptom relief TerminatedThis study tested whether a combination of levocarnitine (an amino acid) and vitamin B complex could help lower high bilirubin levels caused by two leukemia drugs, PEG-asparaginase and inotuzumab ozogamicin. The trial planned to enroll 10 adults with acute lymphoblastic leukemia …
Matched conditions: ACUTE LYMPHOBLASTIC LEUKEMIA
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Symptom relief
Last updated May 26, 2026 03:04 UTC