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New hope for kids with lingering leukemia: targeted drug aims to wipe out hidden cancer cells

NCT ID NCT03913559

First seen Feb 05, 2026 · Last updated May 21, 2026 · Updated 10 times

Summary

This study tested a drug called inotuzumab ozogamicin (Besponsa) in children and young adults with a type of leukemia (B-ALL) that still had small amounts of cancer cells after standard treatment. The drug works like a smart bomb, targeting a protein (CD22) found on most leukemia cells to deliver a powerful toxin. The goal was to see if it could clear those leftover cells and improve outcomes, but the study was stopped early after enrolling only 5 participants.

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Contacts and locations

Locations

  • Rady Children's Hospital San Diego

    San Diego, California, 92123, United States

  • St. Jude Children's Research Hospital

    Memphis, Tennessee, 38105, United States

Conditions

Explore the condition pages connected to this study.