ACUTE-GRAFT-VERSUS-HOST DISEASE
Clinical trials for ACUTE-GRAFT-VERSUS-HOST DISEASE explained in plain language.
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New hope for stem cell transplant patients: lower steroid doses with drug combo
Disease control TerminatedThis study tested a combination of three drugs (ruxolitinib, uhCG/EGF, and steroids) to treat severe acute graft-versus-host disease (GVHD), a serious complication after stem cell transplant. The goal was to find the lowest effective steroid dose to reduce side effects while stil…
Matched conditions: ACUTE-GRAFT-VERSUS-HOST DISEASE
Phase: PHASE1, PHASE2 • Sponsor: Masonic Cancer Center, University of Minnesota • Aim: Disease control
Last updated May 26, 2026 08:25 UTC
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Pediatric GVHD drug combo trial halted early after just 2 kids enrolled
Disease control TerminatedThis study tested a drug called itacitinib combined with steroids to treat a serious complication of stem cell transplants called acute graft-versus-host disease (aGVHD) in children. The trial aimed to see if the combination was safe and effective for kids aged 28 days to under 1…
Matched conditions: ACUTE-GRAFT-VERSUS-HOST DISEASE
Phase: PHASE1, PHASE2 • Sponsor: Incyte Corporation • Aim: Disease control
Last updated May 22, 2026 14:01 UTC