ACUTE-GRAFT-VERSUS-HOST DISEASE
Clinical trials for ACUTE-GRAFT-VERSUS-HOST DISEASE explained in plain language.
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Cord stem cells take on transplant complication
Disease control CompletedThis study tested whether adding umbilical cord stem cells to standard steroid treatment could help people with severe graft-versus-host disease (GVHD), a serious complication after a bone marrow transplant. 26 participants received the stem cells or a placebo along with their us…
Matched conditions: ACUTE-GRAFT-VERSUS-HOST DISEASE
Phase: PHASE1, PHASE2 • Sponsor: Cytopeutics Sdn. Bhd. • Aim: Disease control
Last updated May 26, 2026 08:19 UTC
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Cord stem cells offer hope for dangerous transplant complication
Disease control CompletedThis early-stage study tested a treatment made from umbilical cord stem cells for people with a serious condition called graft-versus-host disease (GVHD), which can happen after a bone marrow or stem cell transplant. The study included 24 adults aged 18 to 75. Researchers gave tw…
Matched conditions: ACUTE-GRAFT-VERSUS-HOST DISEASE
Phase: PHASE1 • Sponsor: University of Kansas Medical Center • Aim: Disease control
Last updated May 20, 2026 11:56 UTC
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Diabetes drug shows promise in preventing deadly transplant complication
Prevention CompletedThis study tested whether sitagliptin, a common diabetes medicine, could prevent acute graft-versus-host disease (GVHD) in 190 adults receiving stem cell transplants from related or unrelated donors. Participants took sitagliptin alongside standard GVHD prevention. The main goal …
Matched conditions: ACUTE-GRAFT-VERSUS-HOST DISEASE
Phase: PHASE3 • Sponsor: The First Affiliated Hospital of Soochow University • Aim: Prevention
Last updated May 22, 2026 14:03 UTC
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New drug aims to stop deadly immune attack after stem cell transplant
Prevention CompletedThis study tested whether a protein called alpha-1 antitrypsin can prevent graft-versus-host disease (GVHD) in people receiving a blood stem cell transplant for blood cancers like leukemia or lymphoma. GVHD happens when donor immune cells attack the patient's body. The trial incl…
Matched conditions: ACUTE-GRAFT-VERSUS-HOST DISEASE
Phase: PHASE2, PHASE3 • Sponsor: CSL Behring • Aim: Prevention
Last updated May 19, 2026 11:59 UTC