ACUTE-GRAFT-VERSUS-HOST DISEASE
Clinical trials for ACUTE-GRAFT-VERSUS-HOST DISEASE explained in plain language.
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Could a simple timing change protect transplant patients?
Disease control OngoingThis study is testing whether the time of day a patient receives donor stem cells can reduce the risk of a dangerous immune reaction called acute graft-versus-host disease (GVHD). It involves about 200 people with blood cancers who are getting a stem cell transplant. Researchers …
Matched conditions: ACUTE-GRAFT-VERSUS-HOST DISEASE
Phase: PHASE3 • Sponsor: Anhui Provincial Hospital • Aim: Disease control
Last updated Apr 02, 2026 14:57 UTC
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Poop pills tested to stop deadly transplant complication
Disease control OngoingThis study is testing whether taking capsules containing processed, healthy stool (fecal microbiota) can prevent severe graft-versus-host disease (GVHD) in adults who have received a bone marrow transplant. GVHD is a serious and common complication where the donor's immune cells …
Matched conditions: ACUTE-GRAFT-VERSUS-HOST DISEASE
Phase: PHASE2 • Sponsor: Fred Hutchinson Cancer Center • Aim: Disease control
Last updated Apr 02, 2026 14:56 UTC
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Could a simple probiotic shield kids from dangerous transplant complication?
Prevention OngoingThis study is testing whether a specific probiotic (Lactobacillus plantarum) can prevent a serious complication called acute graft-versus-host disease (GvHD) in children, teens, and young adults receiving a donor stem cell transplant. GvHD happens when the new donor cells attack …
Matched conditions: ACUTE-GRAFT-VERSUS-HOST DISEASE
Phase: PHASE3 • Sponsor: Children's Oncology Group • Aim: Prevention
Last updated Apr 03, 2026 14:41 UTC
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New treatment aims to stop dangerous transplant complication
Prevention OngoingThis study is testing whether a protein called Alpha-1 Antitrypsin can prevent graft-versus-host disease (GVHD) in patients receiving stem cell transplants for blood cancers. GVHD is a serious complication where the donor's immune cells attack the patient's body. The trial involv…
Matched conditions: ACUTE-GRAFT-VERSUS-HOST DISEASE
Phase: PHASE2, PHASE3 • Sponsor: CSL Behring • Aim: Prevention
Last updated Mar 17, 2026 12:55 UTC
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Scientists probe Skin's immune sentries in transplant complication
Knowledge-focused OngoingThis study aims to understand the role of specific immune cells, called dendritic cells, in the development of skin graft-versus-host disease (GVHD) after a bone marrow transplant. Researchers will collect and analyze small skin samples from 22 adult patients who have either acut…
Matched conditions: ACUTE-GRAFT-VERSUS-HOST DISEASE
Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:41 UTC