ACUTE-GRAFT-VERSUS-HOST DISEASE
Clinical trials for ACUTE-GRAFT-VERSUS-HOST DISEASE explained in plain language.
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Stem cell study to prevent transplant complications withdrawn
Disease control TerminatedThis study aimed to see if a special type of stem cell (hAESC) could safely prevent acute graft-versus-host disease (aGVHD) in people receiving a stem cell transplant for blood cancer. The trial was withdrawn before any participants were enrolled, so no results are available. The…
Matched conditions: ACUTE-GRAFT-VERSUS-HOST DISEASE
Phase: PHASE1 • Sponsor: Nanfang Hospital, Southern Medical University • Aim: Disease control
Last updated May 26, 2026 08:28 UTC
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New combo therapy aims to tame transplant complication
Disease control OngoingThis early-phase study tests whether a low dose of steroids combined with the drug ruxolitinib can safely control grade II acute graft-versus-host disease (aGVHD) after a stem cell transplant. The trial involves 30 people with blood cancers who have received a donor stem cell tra…
Matched conditions: ACUTE-GRAFT-VERSUS-HOST DISEASE
Phase: PHASE1 • Sponsor: Daihong Liu • Aim: Disease control
Last updated May 26, 2026 08:27 UTC
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Poop pills may shield stem cell patients from deadly complication
Prevention OngoingThis study tests whether giving patients processed fecal material (fecal microbiota transplantation) by mouth after a stem cell transplant can prevent severe graft-versus-host disease (GVHD), a serious complication where donor cells attack the patient's body. The trial involves 1…
Matched conditions: ACUTE-GRAFT-VERSUS-HOST DISEASE
Phase: PHASE2 • Sponsor: Fred Hutchinson Cancer Center • Aim: Prevention
Last updated May 26, 2026 08:26 UTC
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Probiotic shows promise in preventing deadly transplant complication in kids
Prevention OngoingThis study tests whether a probiotic called Lactobacillus plantarum can prevent a serious gut condition called graft-versus-host disease (GvHD) in children receiving a donor stem cell transplant. About 173 children with blood cancers or other blood disorders are taking part. The …
Matched conditions: ACUTE-GRAFT-VERSUS-HOST DISEASE
Phase: PHASE3 • Sponsor: Children's Oncology Group • Aim: Prevention
Last updated May 18, 2026 12:02 UTC
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Scientists probe skin cells to unravel GVHD mystery
Knowledge-focused OngoingThis study looks at how different types of immune cells (dendritic cells) in the skin are involved in graft-versus-host disease (GVHD) after a bone marrow transplant. Researchers will collect skin samples and blood from 22 adults with acute or chronic skin GVHD to analyze cell ty…
Matched conditions: ACUTE-GRAFT-VERSUS-HOST DISEASE
Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated May 18, 2026 12:12 UTC
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Timing matters: new study tests if stem cell infusion time can prevent transplant complications
Knowledge-focused OngoingThis study tests whether the time of day stem cells are given affects the risk of acute graft-versus-host disease (aGVHD) in blood cancer patients receiving a stem cell transplant. About 198 patients aged 12-60 will be randomly assigned to receive their infusion at different time…
Matched conditions: ACUTE-GRAFT-VERSUS-HOST DISEASE
Phase: PHASE3 • Sponsor: Anhui Provincial Hospital • Aim: Knowledge-focused
Last updated May 15, 2026 12:06 UTC