ACUTE-GRAFT-VERSUS-HOST DISEASE
Clinical trials for ACUTE-GRAFT-VERSUS-HOST DISEASE explained in plain language.
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New hope for stem cell transplant patients: experimental drug targets severe immune reaction
Disease control Recruiting nowThis early-stage trial tests an experimental drug called AC-003 in 24 adults who developed severe graft-versus-host disease (aGVHD) after a stem cell transplant and did not respond to standard steroids. The main goal is to check the drug's safety and how the body processes it, wh…
Matched conditions: ACUTE-GRAFT-VERSUS-HOST DISEASE
Phase: PHASE1 • Sponsor: Accro Bioscience (Suzhou) Limited • Aim: Disease control
Last updated May 26, 2026 08:42 UTC
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Timing is everything: can stem cell infusion schedule tame transplant complications?
Disease control Recruiting nowThis study looks at whether changing when stem cells are given after a cord blood transplant can reduce the chance of a severe immune reaction called graft-versus-host disease (GVHD). About 134 people with blood cancers who are getting their first cord blood transplant will take …
Matched conditions: ACUTE-GRAFT-VERSUS-HOST DISEASE
Phase: PHASE3 • Sponsor: Anhui Provincial Hospital • Aim: Disease control
Last updated May 26, 2026 08:40 UTC
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New hope for transplant patients: drug combo may tame deadly immune attack
Disease control Recruiting nowThis study tests a drug called ruxolitinib for treating acute graft-versus-host disease (GVHD), a serious condition where donor cells attack the patient's body after a bone marrow transplant. About 98 adults with moderate to severe GVHD will receive either ruxolitinib alone or wi…
Matched conditions: ACUTE-GRAFT-VERSUS-HOST DISEASE
Phase: PHASE2 • Sponsor: John Levine • Aim: Disease control
Last updated May 26, 2026 08:32 UTC
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New hope for stem cell transplant patients: drug combo targets GVHD
Disease control Recruiting nowThis study tests a new drug called gecacitinib (jaktinib) combined with standard steroids as a first treatment for acute graft-versus-host disease (GVHD) in people who had a stem cell transplant. GVHD is a serious condition where donor cells attack the patient's body. The trial w…
Matched conditions: ACUTE-GRAFT-VERSUS-HOST DISEASE
Phase: PHASE1, PHASE2 • Sponsor: First Affiliated Hospital of Zhejiang University • Aim: Disease control
Last updated May 19, 2026 12:00 UTC
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Toothbrush vs. transplant complication: can a simple cleaning prevent a deadly side effect?
Prevention Recruiting nowThis study tests whether a dental cleaning shortly after a stem cell transplant can prevent chronic graft-versus-host disease (GVHD), a serious condition where donor cells attack the patient's body. About 45 adults receiving a stem cell transplant for blood cancer will get a post…
Matched conditions: ACUTE-GRAFT-VERSUS-HOST DISEASE
Phase: NA • Sponsor: Fred Hutchinson Cancer Center • Aim: Prevention
Last updated May 14, 2026 12:06 UTC
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Ancient heat therapy may ease Life-Threatening transplant complication
Symptom relief Recruiting nowThis study tests whether moxibustion—a traditional therapy that burns herbs near the skin—can help people with severe gut problems after a stem cell transplant. About 42 patients whose graft-versus-host disease did not respond to steroids will receive standard drugs plus daily mo…
Matched conditions: ACUTE-GRAFT-VERSUS-HOST DISEASE
Phase: PHASE2 • Sponsor: Union Hospital, Tongji Medical College, Huazhong University of Science and Technology • Aim: Symptom relief
Last updated May 22, 2026 14:05 UTC
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Exercise may ease steroid side effects in transplant patients
Symptom relief Recruiting nowThis study looks at whether a home-based exercise program (aerobic and resistance training) is practical and helpful for adults who develop graft-versus-host disease after a stem cell transplant and are starting high-dose steroids. About 36 participants will either do the exercis…
Matched conditions: ACUTE-GRAFT-VERSUS-HOST DISEASE
Phase: NA • Sponsor: Dana-Farber Cancer Institute • Aim: Symptom relief
Last updated May 20, 2026 11:56 UTC