ACUTE-GRAFT-VERSUS-HOST DISEASE
Clinical trials for ACUTE-GRAFT-VERSUS-HOST DISEASE explained in plain language.
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New approach tested for dangerous transplant complication
Disease control Recruiting nowThis study is testing a drug called ruxolitinib as the first treatment for acute graft-versus-host disease (GVHD), a serious complication that can occur after a bone marrow transplant. Researchers want to see if ruxolitinib alone works as well as steroid-free therapy for lower-ri…
Matched conditions: ACUTE-GRAFT-VERSUS-HOST DISEASE
Phase: PHASE2 • Sponsor: John Levine • Aim: Disease control
Last updated Apr 03, 2026 14:42 UTC
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New drug tested for dangerous transplant complication
Disease control Recruiting nowThis early-stage trial is testing a new oral capsule called AC-003 in patients with severe, steroid-resistant acute Graft-Versus-Host Disease (aGVHD). The study aims to find a safe dose and see if the drug can help control this serious complication that occurs after a stem cell t…
Matched conditions: ACUTE-GRAFT-VERSUS-HOST DISEASE
Phase: PHASE1 • Sponsor: Accro Bioscience (Suzhou) Limited • Aim: Disease control
Last updated Apr 03, 2026 14:41 UTC
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Could a simple change in transplant timing reduce dangerous side effects?
Disease control Recruiting nowThis study is testing whether the time of day a patient receives a cord blood stem cell transplant affects their risk of developing a serious complication called acute graft-versus-host disease (GVHD). It will involve 134 adults with blood cancers who are getting their first tran…
Matched conditions: ACUTE-GRAFT-VERSUS-HOST DISEASE
Phase: PHASE3 • Sponsor: Anhui Provincial Hospital • Aim: Disease control
Last updated Apr 03, 2026 14:41 UTC
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New hope for stem cell transplant patients battling dangerous complication
Disease control Recruiting nowThis study is testing a new drug called gecacitinib, combined with standard steroid treatment, for patients who develop a severe immune reaction called acute graft-versus-host disease after a stem cell transplant. The trial aims to find the safest and most effective dose and see …
Matched conditions: ACUTE-GRAFT-VERSUS-HOST DISEASE
Phase: PHASE1, PHASE2 • Sponsor: First Affiliated Hospital of Zhejiang University • Aim: Disease control
Last updated Mar 27, 2026 12:40 UTC
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Can exercise fight steroid side effects for transplant patients?
Symptom relief Recruiting nowThis study is testing if a home-based exercise program can help patients who develop Graft-Versus-Host Disease (GVHD) after a stem cell transplant. The goal is to see if exercise can improve blood sugar control, body composition, fitness, and quality of life while patients are on…
Matched conditions: ACUTE-GRAFT-VERSUS-HOST DISEASE
Phase: NA • Sponsor: Dana-Farber Cancer Institute • Aim: Symptom relief
Last updated Mar 20, 2026 14:48 UTC