ACUTE CORONARY SYNDROMES (ACS)

This study tests whether a drug-coated balloon can reduce fatty buildup in heart artery plaques better than standard medications alone. Researchers will enroll 400 adults with acute coronary syndrome. Participants will be randomly assigned to receive either the balloon treatment …

This Phase 1 study compares a new investigational drug, CG-0255, to the standard blood thinner Plavix in 136 healthy adults aged 18-55. The goal is to see how the body absorbs and processes each drug and how well they prevent blood clotting. Participants will receive either CG-02…

This study looks at 326 adults who had a heart attack and have a rare condition where their heart arteries are abnormally widened (coronary artery ectasia). It compares the standard treatment of two anti-clotting drugs (aspirin and clopidogrel) against one anti-clotting drug plus…

This study tests whether placing stents in non-blocking but unstable heart plaques, along with intensive medication, reduces heart attacks and other cardiac events better than medication alone. About 2,190 adults with acute coronary syndrome will be randomly assigned to either st…

This study compares two ways to guide heart stent placement in people with acute coronary syndrome (unstable angina or heart attack). One method uses standard X-ray images (angiography), and the other adds an ultrasound probe inside the artery (IVUS) for more detail. About 1,500 …

This study tests a new CT scan that works without an ECG to quickly check for heart disease in people with chest pain and high troponin levels. About 230 adults will get this scan plus the standard invasive test to see if the new method is accurate. If successful, it could reduce…

This study tests a new rapid blood test that can detect heart attacks in about one hour, right in the doctor's office. Researchers will enroll 2,500 adults with chest pain at six Norwegian clinics. The goal is to see if the test safely rules out heart attacks, reduces unnecessary…

This study tests if fexuprazan can prevent upper stomach bleeding in 400 heart patients at high risk for bleeding who must take two blood thinners after getting a heart stent. Participants receive either fexuprazan or the standard drug lansoprazole daily for 6 months. The goal is…

This study tests whether getting a flu vaccine can prevent serious heart problems in people who have recently had a heart attack or unstable angina. About 6,620 participants will receive either a flu shot or a placebo and be followed for one year. The goal is to see if the vaccin…

This study is testing whether a single intravenous dose of iron can improve quality of life and reduce frailty in adults aged 65 and older who have iron deficiency after a heart attack. About 538 participants will be randomly assigned to receive either the iron infusion or standa…

This study looks at 60 adult male smokers under 65 who have both heart disease (acute coronary syndrome) and pneumonia along with COPD. Researchers want to see if certain blood markers (GDF-15, MR proADM, and Presepsin) change after getting a flu shot. The goal is to understand h…

This study examines gut health in 15 adults aged 30-70 who have had a heart attack or unstable angina. Researchers will measure gut permeability and bacteria imbalances at the start and after 24 hours. Then, they will test if special essential oils can restore healthy gut functio…