Vitamin B12 deficiency
MONDO:0020696A disease characterized by low serum levels of vitamin B12, either inherited or acquired.
Also known as: cobalamin deficiency, hypocobalaminemia, vitamin b12 deficiency
26 clinical trials for this condition and its sub-types, 12 tagged with Vitamin B12 deficiency itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Vitamin B12 deficiency
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Inborn disorder of cobalamin metabolism and transport 1 trial · 3 incl. sub-types
9 sub-types
- Methylmalonic aciduria and homocystinuria 1 trial · 3 incl. sub-types Sub-types →
- Homocystinuria without methylmalonic aciduria 0 trials · 2 incl. sub-types Sub-types →
- Methylmalonic aciduria and/or homocystinuria, cblD type 0 trials · 2 incl. sub-types Sub-types →
- Vitamin B12-responsive methylmalonic acidemia 0 trials · 2 incl. sub-types Sub-types →
- Hereditary intrinsic factor deficiency 1 trial Sub-types →
- Transcobalamin II deficiency 1 trial
- Imerslund-Grasbeck syndrome 0 trials Sub-types →
- Methylmalonic acidemia due to transcobalamin receptor defect 0 trials
- Transcobalamin I deficiency 0 trials
Most studied deeper sub-types
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Can an injection beat pills for vitamin B12 deficiency?
Disease control CompletedThis trial tests whether an injected mix of vitamins B6, B12, and folic acid raises vitamin B12 levels better than standard oral B12 tablets in adults with B12 deficiency. Researchers measure blood markers of B12 status and methylation capacity after 4 weeks of treatment. They al…
Phase 4 • Sponsor: Medice Arzneimittel Pütter GmbH & Co KG • Aim: Disease control
Last updated Sep 06, 2026 00:00 UTC
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Can an IV boost beat pills for B12 deficiency in kidney dialysis?
Disease control CompletedThis trial asks whether an intravenous (IV) injection of vitamin B12 works better than oral tablets to correct B12 deficiency in adults on long-term hemodialysis. Participants receive either a weekly IV dose after dialysis or oral tablets three times a day for four weeks. Researc…
Sponsor: Jinnah Hospital • Aim: Disease control
Last updated Aug 26, 2026 00:00 UTC
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New scoring system aims to cut child deaths from malnutrition in chad
Disease control CompletedThis study tested a simple scoring system called RISQ to help healthcare workers quickly identify which severely malnourished children are most at risk of dying. Over 14,600 children aged 6 to 59 months in Chad took part. The goal was to see if using the RISQ system could lower d…
Sponsor: The Hospital for Sick Children • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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Can cookies fight malnutrition? new study tests a tasty solution
Disease control CompletedThis study tested whether special cookies made from soy, chickpea, and peanut flour could improve the health of malnourished children. Sixty children aged 3 to 10 years were split into two groups: one group ate the cookies daily for three months along with their regular diet, whi…
Sponsor: Mairaj Noor • Aim: Disease control
Last updated Jun 27, 2026 12:02 UTC
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Could a daily vitamin fix B12 deficiency in diabetes patients?
Disease control CompletedThis study tested whether a special oral vitamin B12 supplement (Sucrosomial® B12) can raise B12 levels in people with type 2 diabetes who have low B12 due to taking metformin. Fifty adults took either the supplement or a placebo daily for 3 weeks. The goal was to see if the supp…
Sponsor: Liaquat University of Medical & Health Sciences • Aim: Disease control
Last updated Jun 27, 2026 08:03 UTC
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Searching for biomarkers to combat malnutrition
Knowledge-focused CompletedThis study aims to identify biological markers of malnutrition by analyzing blood, saliva, and stool samples from 2,000 people, including those with malnutrition and healthy controls. Researchers will use advanced techniques to examine genetic, microbial, and metabolic profiles. …
Sponsor: Federico II University • Aim: Knowledge-focused
Last updated Sep 03, 2026 00:00 UTC
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Local cereals fortified with vitamins could boost teen health in rural ethiopia
Knowledge-focused CompletedThis study looked at whether adding folic acid and vitamin B12 to locally made cereals can improve the nutrition, thinking skills, and mood of teenage girls in rural Ethiopia. About 472 girls aged 13-19 took part. The goal was to see if small-scale food fortification can help pre…
Sponsor: University Ghent • Aim: Knowledge-focused
Last updated Aug 16, 2026 00:00 UTC
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Could fibromyalgia drugs drain your B12?
Knowledge-focused CompletedThis completed study from Turkey examined vitamin B12 and folic acid levels in 104 fibromyalgia patients before and after they started antiepileptic treatment. Researchers wanted to see if these drugs, already known to lower B12 and folate in epilepsy patients, have the same effe…
Sponsor: Gaziosmanpasa Research and Education Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:14 UTC
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Hidden gut infections may sabotage TB recovery, study suggests
Knowledge-focused CompletedThis completed study looked at 141 people being treated for tuberculosis (TB) to see if intestinal parasites or poor nutrition made their recovery harder. Researchers checked stool samples for parasites and measured weight gain and treatment success. Some participants received nu…
Sponsor: Boston Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC
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Nerve pain pills may lower key vitamins, study finds
Knowledge-focused CompletedThis study looked at vitamin B12 and folic acid levels in 96 people with nerve pain before and after they started taking antiepileptic drugs. The goal was to see if these medications lower important vitamin levels. No new treatment was tested; the researchers simply reviewed past…
Sponsor: Gaziosmanpasa Research and Education Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC
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Beef for brainpower: study tests 30-Day diet on young Women's cognition
Knowledge-focused CompletedThis study looked at whether eating beef every day for 30 days could improve thinking and visual skills in healthy young women. 80 women aged 18-40 took part, with one group eating beef and the other eating a plant-based protein. Researchers measured their performance on a 3D tra…
Sponsor: Texas A&M University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC