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Can a simple vitamin pill fix B12 deficiency in diabetes patients?

NCT ID NCT06983223

First seen Nov 01, 2025 · Last updated Jun 21, 2026 · Updated 33 times

Summary

This study tested whether an oral vitamin B12 supplement (Sucrosomial® B12) can raise B12 levels in people with type 2 diabetes who have low B12 due to taking metformin. Fifty adults took either the supplement or a placebo daily for three weeks. Researchers measured changes in blood B12 levels and related markers.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Liaquat University of Medical & Health Sciences (LUMHS)

    Jāmshoro, Sindh, 76090, Pakistan

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Sucrosomial® Vitamin B12 (an oral vitamin B12 supplement)

What this could lead to

If it works, this could offer a simple, daily supplement to correct B12 deficiency in people with diabetes who take metformin.

What could go wrong

This is a small, completed trial with only 50 participants. Results may not apply to everyone, and the supplement may not work better than a placebo.

Conditions

The condition(s) this trial relates to.

type 2 diabetes mellitus vitamin B12 deficiency

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.