Vascular occlusion disorder

This study is testing a device called WRAPSODY CIE, a mesh tube placed in veins used for dialysis. The goal is to see if it can keep these veins from narrowing or blocking over time. Researchers will follow 250 people on dialysis for up to 3 years to check how well the device wor…

This study tests a new catheter system designed to remove blockages in leg veins caused by old blood clots. About 20 adults with painful swelling or pain from chronic vein blockages will receive the treatment. The main goals are to ensure the procedure is safe and to check if it …

This study tests whether the antibiotic minocycline can improve recovery in people who have had a major stroke and undergone a procedure to remove a blood clot from a large brain artery. Even when the clot is successfully removed, many patients still have significant disability. …

This study is testing a new device called the Recana Thrombectomy Catheter System to treat chronic blockages in veins. It will include 30 adults with symptoms like leg swelling or pain due to venous obstruction. The device is inserted into the vein to remove the blockage and rest…

This trial tests a new drug-coated stent called Solaris DE for dialysis patients whose veins become narrowed or blocked. About 120 participants will either receive the stent plus balloon angioplasty or angioplasty alone. The goal is to see if the stent keeps the vein open longer …

This study tests a new way to reduce heart damage after a severe heart attack (STEMI). Doctors will cool the heart's arteries during the standard procedure to open blocked vessels. The goal is to see if this cooling prevents further injury and improves heart function. The trial i…

This Phase 3 trial tests whether a new contrast agent called gadopiclenol works as well as the standard agent (Dotarem) for MRI scans to find blocked arteries in the neck, legs, or abdomen. About 315 adults with suspected vascular disease will receive both agents in random order …

This study tests whether a quick, routine ultrasound measurement (called the resistance index) can accurately identify people with narrowed neck arteries who have normal brain blood flow response. If it works, many patients could avoid a time-consuming, specialized test. The stud…

This trial tests whether using a wrist artery access point closer to the hand (distal radial) is safer than the usual wrist access for complex heart procedures like opening blocked arteries. About 708 adults with stable or unstable heart conditions will be randomly assigned to on…

This pilot study aims to understand how a nerve block injection affects jaw muscle activity and bite force in 20 healthy adults. Participants receive one injection, and measurements are taken before and after. The goal is to gather information, not to treat any disease.