Vascular insufficiency disorder
MONDO:0020674Also known as: vascular insufficiency
244 clinical trials for this condition and its sub-types, 1 tagged with Vascular insufficiency disorder itself.
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Sub-types of Vascular insufficiency disorder
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Venous insufficiency 50 trials · 98 incl. sub-types
2 sub-types
- Chronic venous insufficiency 59 trials
- Post-thrombotic syndrome 13 trials
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Tricuspid valve insufficiency 83 trials
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Aortic valve insufficiency 56 trials
1 sub-type
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Vertebrobasilar insufficiency 7 trials
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Vertebral artery insufficiency 2 trials
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Basilar artery insufficiency 0 trials
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Splenic infarction 0 trials
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Glue vs. heat vs. knife: which vein fix wins?
Disease control Stopped earlyThis study tested a medical glue called VenaSeal against heat therapy or surgery for treating venous reflux, a condition where leg veins don't pump blood properly. About 500 adults with early to advanced vein disease took part. The goal was to see which method patients liked more…
Sponsor: Medtronic Endovascular • Aim: Disease control
Last updated Aug 27, 2026 00:00 UTC
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Can a less invasive valve replacement tame a failing aortic valve?
Disease control Stopped earlyThis study is a patient registry that collects information on people with severe aortic stenosis or aortic regurgitation who are treated with the Trilogy heart valve system, a device implanted via a catheter (TAVI) to replace the aortic valve without open-heart surgery. The goal …
Sponsor: JenaValve Technology, Inc. • Aim: Disease control
Last updated Aug 23, 2026 00:00 UTC
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Experimental vein valve repair device tested in 14 patients, trial halted early
Disease control Stopped earlyThis study tested a device called the BlueLeaf System to fix faulty valves in leg veins of people with chronic venous insufficiency (CVI). The goal was to see if it could safely reduce backward blood flow and improve symptoms. Only 14 people took part before the trial was stopped…
Sponsor: Intervene, Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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Varicose vein treatment showdown: foam vs. heat
Symptom relief Stopped earlyThis study compared two treatments for varicose veins: Varithena (a foam) and Endothermal Ablation (using heat). It included 43 adults with a faulty great saphenous vein. The goal was to see which treatment better reduced symptoms like heaviness and pain over 3 months.
Phase 4 • Sponsor: Boston Scientific Corporation • Aim: Symptom relief
Last updated Jun 27, 2026 11:03 UTC
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New wound pump shows promise for stubborn leg ulcers
Symptom relief Stopped earlyThis study tested whether a single-use negative pressure wound therapy system (PICO) helps heal hard-to-treat venous leg ulcers better than standard care. About 142 adults with leg ulcers that had lasted at least 6 weeks took part. The main goal was to see if more ulcers healed c…
Sponsor: Smith & Nephew, Inc. • Aim: Symptom relief
Last updated Jun 27, 2026 08:09 UTC
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Massive german study compares new and old heart valve procedures
Knowledge-focused Stopped earlyThis study was a large registry that planned to follow 180,000 patients in Germany with aortic valve problems (leaky or narrowed valves). The goal was to compare newer, less invasive treatments like TAVI with standard open-heart surgery to see which works best and for whom. Resea…
Sponsor: German Aortic Valve Registry • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC