Urethral obstruction

This trial compares three different laser frequency settings (40, 50, and 60 Hz) used during a procedure called HoLEP, which treats enlarged prostates causing bothersome urinary symptoms. Men aged 18-89 undergoing HoLEP will be randomly assigned to one of the laser settings on th…

This pilot study tested a bioengineered collagen scaffold as a substitute for the traditional mouth-tissue graft used in urethral stricture repair. Five adult men with a short urethral stricture (less than 3 cm) received the implant. The main goal was to see if the urethra stayed…

This study tested a special balloon coated with the drug paclitaxel to treat urethral stricture, a narrowing of the tube that carries urine out of the body. Sixteen men with recurrent strictures received the balloon treatment. The goal was to see if the device is safe and can hel…

Surgeons often take a small piece of tissue from inside the mouth to rebuild the urethra in men with a narrowed urine tube. This leaves a raw patch in the mouth that can be painful and slow to heal. Researchers are testing whether covering that mouth wound with a biological dress…

This study looks at three different numbing methods to reduce pain in the mouth after a type of urethral surgery called buccal graft urethroplasty. Sixty men will be randomly assigned to one of the methods, and their pain levels and need for painkillers will be tracked. The goal …

This study compared two ways to treat a narrow urethra (the tube that carries urine out of the body) in 60 men aged 18 to 70. One method uses a laser, the other a cold knife. The goal was to see which works better at improving urine flow after 30 days. The findings could help sta…

This study looks back at 250 patients who had surgery to widen a narrowed urethra using a graft from the inside of the cheek. The goal is to identify factors that predict whether the narrowing will return. Researchers will review medical records from the past 10 years, focusing o…