Tourette syndrome

This study follows 300 adults with Parkinson's disease, essential tremor, or dystonia who receive deep brain stimulation (DBS). DBS uses a device implanted in the chest to send electrical pulses to brain areas controlling movement. Researchers will track symptom severity, medicat…

This study will test a traditional Chinese herbal formula called Pei Tu Ning Feng Tang in 60 children aged 4 to 15 with Tourette syndrome. Researchers will measure changes in tic severity, brain activity using a special light-based scanner, and markers in blood and stool. The goa…

This study tests whether adding a gentle magnetic brain stimulation (TMS) to a standard behavioral therapy (CBIT) can help teens and young adults with chronic tics or Tourette syndrome better control their tics. About 60 participants aged 12–21 will receive either CBIT alone or C…

This study follows 20 adults with severe, drug-resistant Tourette syndrome who receive deep brain stimulation (DBS) targeting a specific brain region. Researchers will check tic severity, mental health, and quality of life every year for five years after surgery. The goal is to u…

This trial tests whether a therapy that blends Exposure and Response Prevention (ERP) with Habit Reversal Training (HbRT) can reduce both obsessive-compulsive and tic symptoms in adults with Tourettic OCD — a subtype where OCD and tic disorders overlap. Standard treatments usuall…

This trial tests whether sertraline, a widely used antidepressant, can reduce anxiety in children and teens aged 8 to 17 with neurodevelopmental disorders such as autism, ADHD, Fragile X syndrome, and Tourette syndrome. Participants receive either sertraline or a placebo for seve…

This study tests whether a structured behavioral therapy called CBIT can help children and teens aged 10–17 with chronic tics (Tourette syndrome or persistent tic disorder) gain better control over their symptoms. Participants receive 8 weekly CBIT sessions, learning to replace t…

This study tests whether real-time fMRI neurofeedback can help teens aged 10-16 with Tourette Syndrome reduce their tics. Participants learn to control activity in a brain region linked to tics by watching their own brain activity on a screen. The trial compares this to a control…

This program provides early access to ecopipam for children, teens, and adults aged 6 to 50 with Tourette's disorder. The goal is to see if the drug is safe and tolerable over the long term, while also tracking quality of life. Participants receive the medication under their doct…

This study tests whether a mindfulness-based program can help adults with Tourette syndrome or persistent tic disorders reduce their tics. Participants will either learn mindfulness techniques to manage urges or receive standard relaxation and coping support. The goal is to see w…

This study is testing a behavioral treatment called CBIT (Comprehensive Behavioral Intervention for Tics) in 200 youth who have tic disorders, such as Tourette's, along with related emotional problems like anxiety or depression. The goal is to see if CBIT can reduce tic severity …

This study in Norway is testing whether nature-based group activities—like outdoor education and therapy—can improve quality of life for 240 children and youth with ADHD, autism, or Tourette's. Participants will take part in 10- to 12-week programs in schools or healthcare settin…

This study tracks how tic symptoms change in 30 youth aged 12-17 with Tourette syndrome or chronic tic disorders. Participants receive 8 sessions of behavioral therapy (CBIT) and complete daily surveys, wear a device to track physiology, and perform weekly tasks. The goal is to i…

This study follows 140 adults with Tourette syndrome for two years to see how stress from life events impacts tic severity, depression, anxiety, and quality of life. Participants complete interviews and questionnaires about their tics, mood, and daily functioning. The goal is to …

This study is creating a shared database of children who have received deep brain stimulation (DBS) for movement disorders like dystonia, epilepsy, or Tourette syndrome. By pooling data from multiple hospitals, researchers hope to answer key questions about who benefits most and …

This study aims to better understand sensory symptoms in adults with Tourette syndrome or chronic tic disorders. About 214 participants will fill out yearly questionnaires about urges, attention, mood, and quality of life. The goal is to gather information, not to test a treatmen…

This study looks at how often people with Tourette syndrome have trouble being assertive and managing emotions. About 350 adults with Tourette syndrome will fill out online surveys about their symptoms, quality of life, and mood. The goal is to better understand these challenges,…

This study looks at 50 people with OCD or Tourette syndrome to find clear differences between compulsions and tics. Participants wear a smartwatch and a portable brain-wave recorder at home and in the lab. The goal is to help doctors choose the right treatment by using objective …

This research study collects health information from 10,000 people with brain inflammation conditions like Long COVID, ME/CFS, and autoimmune diseases. Participants use a smartphone app to share symptoms, health history, and wearable data. The goal is to find disease subtypes and…

This study aims to learn more about sensory and movement difficulties in adolescents with tic disorders, like Tourette syndrome. Researchers will compare teens with and without tics using questionnaires, brain wave tests, and motor tasks. The goal is to identify factors that affe…