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Can mindfulness tame tics? new study tests a Drug-Free approach

NCT ID NCT06408662

Symptom relief Sponsor: Johns Hopkins University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tests whether a mindfulness-based program can help adults with Tourette syndrome or persistent tic disorders reduce their tics. Participants will either learn mindfulness techniques to manage urges or receive standard relaxation and coping support. The goal is to see which approach better lowers tic severity and improves daily life.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
mindfulness-based intervention for tics (MBIT)
What this could lead to
If it works, this could offer a new, non-drug way to help people with tics feel more in control and reduce tic severity.
What could go wrong
This is an early-stage study with 150 participants, so results may not apply to everyone. The mindfulness approach may not work for all types of tics or may be less effective than existing treatments.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 150 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2024

Expected to finish

Dec 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. be ≥18 years of age; 2. meet diagnostic criteria for a primary or co-primary diagnosis of Tourette Syndrome or a Persistent Motor or Vocal Tic Disorder on a structured clinical interview; 3. have moderate or greater tic severity as evidenced by a YGTSS Total Tic Score of \>14 (when motor and vocal tics are present) or \>10 (when only motor or vocal tics are present); 4. be medication free and/or on a stable dose of psychiatric medication 8 weeks prior to study participation; 5. be not engaged in psychotherapy for non-TS conditions and/or be on a stable course of therapy for 6 months prior to study participation 6. be fluent in English; 7. have access to a smart phone and/or tablet. Exclusion Criteria: 1. a current diagnosis of substance use disorder, psychosis, mania or another condition that requires another form of care; 2. severe current suicidal/homicidal ideation and/or self-injury requiring medical intervention; 3. concurrent psychotherapy for TS; 4. prior extensive experience with mindfulness and/or meditation.

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Conditions

The condition(s) this trial relates to.

chronic tic disorder tic disorder Tourette syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Chronic motor tic disorder Chronic vocal tic disorder Persistent motor tic disorder Persistent tic disorder Persistent vocal tic disorder Tic disorders Tourette syndrome Tourette's disorder

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Johns Hopkins University School of Medicine

    RECRUITING

    Baltimore, Maryland, 21287, United States

More trials for these conditions

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