Tinnitus

This study will test hyperbaric oxygen therapy (HBOT) — breathing pure oxygen in a pressurized chamber — for over 30 conditions, including long COVID, Crohn's disease, frostbite, and multiple sclerosis. Researchers will track 100 patients to see if HBOT improves their quality of …

This study tests whether artificial intelligence (AI) can accurately help diagnose and triage patients with hearing loss and tinnitus, conditions affecting millions in the UK. Researchers will compare AI recommendations to those made by ear, nose, and throat doctors for 1,500 adu…

Researchers at the University of Zurich are testing whether neurofeedback can ease chronic tinnitus, the persistent ringing or buzzing that affects hearing and quality of life. The study enrolls 24 adults with moderate to severe tinnitus for about nine months. Participants attend…

Researchers are testing whether a one-time injection of an experimental drug called paliroden into the middle ear is safe and can help adults with chronic, constant tinnitus in both ears. Participants, ages 18 to 75, have normal hearing thresholds but struggle to understand speec…

This trial tests whether a gentle electrical pulse to the ear, called transcutaneous auricular vagus nerve stimulation, combined with music tailored to each person's tinnitus, can ease the constant ringing or buzzing of chronic subjective tinnitus. Researchers will compare this c…

This Phase 2a trial is testing an experimental drug called TRTL-913 to see if it is safe and might help reduce tinnitus, the perception of ringing or buzzing in the ears. The study has two parts: first, healthy adults will receive the drug or a placebo to check safety and how the…

This trial tests whether an 8-week internet-based cognitive behavioral therapy for insomnia (CBT-I) can reduce the distress caused by tinnitus compared with standard patient education. About 168 adults with chronic tinnitus and poor sleep will be randomly assigned to one of the t…

This trial tests whether hands-on manual therapy, tinnitus retraining therapy, or a combination of both can reduce the severity and daily impact of somatosensory tinnitus — a type of ringing in the ears that can be triggered by neck, jaw, or head movements. Sixty-five adults with…

This study looks at whether a special noise-generator feature built into Sonova hearing aids can make tinnitus less annoying for people with hearing loss. About 170 adults with chronic tinnitus (lasting at least 6 months) who already use these hearing aids will rate their annoyan…

This study compares real acupuncture to a sham (fake) version in 226 adults with chronic tinnitus (ringing in the ears lasting at least 6 months). Participants receive 10 sessions over 5 weeks. The main goal is to see if real acupuncture reduces tinnitus-related handicap more tha…

This study investigates whether wet cupping therapy can help adults with chronic subjective tinnitus (persistent ringing or buzzing in the ears). Participants aged 21 to 65 with tinnitus lasting over six months are randomly assigned to receive either wet cupping plus usual care o…

This study compares sound therapy, cognitive behavioral therapy (CBT), and their combination to help people with chronic tinnitus (ringing in the ears). Sixty adults aged 18-65 with stable health will be randomly assigned to one of three groups for six weeks. The goal is to see w…

Many people with migraine also suffer from tinnitus, a persistent ringing in the ears. This trial will compare two types of migraine preventives—newer anti-CGRP drugs and older medications like antidepressants and blood pressure drugs—to see which better reduces tinnitus symptoms…

This study tests whether a cochlear implant placed just outside the inner ear, near the round window, can safely reduce severe tinnitus that has not responded to standard treatments. Six adults with long-term, high-impact tinnitus will receive the implant in a two-step procedure.…

This study tests whether manual acupuncture can reduce the burden of acute tinnitus compared to sham acupuncture or usual care. Researchers will enroll 180 adults with bothersome tinnitus lasting 2 weeks to 6 months. Participants receive 10 sessions over 4 weeks, and outcomes foc…

This study tests a coordinated rehab program for 74 veterans with head and neck cancer. The program combines standard swallowing therapy with proactive hearing and balance checks and a nurse assessment to find other rehab needs. The goal is to reduce stress and improve well-being…

This study tests a conversational AI system called Fudan Tinnitus Doctor (FTD) for adults with chronic tinnitus. About 256 participants will use either the AI chatbot or a standard digital education program for 30 days. Researchers will measure changes in tinnitus severity, sleep…

This study tests whether acupuncture can reduce the severity of chronic tinnitus (ringing in the ears) in adults. Researchers will compare 72 tinnitus patients with healthy volunteers, and track changes in symptoms and brain activity after 10 acupuncture sessions. The goal is to …

This study tests whether injecting a small amount of lidocaine (a numbing medicine) around the ear and jaw can reduce tinnitus severity and related disability. Thirty adults with normal hearing and no other ear conditions will receive the injections and be followed for three mont…

This study tests whether combining physiotherapy, structured exercise, and psychological support can reduce the burden of chronic tinnitus (ringing in the ears) in 160 adults aged 18-70. Participants will be randomly assigned to either the 8-week multimodal program or a control g…

This study tests if a new treatment—mild nerve stimulation on the ear plus personalized music—can reduce the annoyance of chronic tinnitus (ringing in the ears) better than standard therapy. About 386 adults with bothersome tinnitus for at least 6 months will be randomly assigned…

This study tests whether umPEALUT, a supplement that reduces inflammation, can help people with tinnitus. The researchers believe that inflammation in the ear and brain may cause or worsen the phantom sounds. One hundred adults with tinnitus will receive either the supplement or …

This study investigates the connection between temporomandibular joint (TMJ) disorders and tinnitus (ringing in the ears). Researchers will use 3D jaw imaging and hearing tests in 50 adults to see if jaw bone shape and arthritis are linked to tinnitus. The goal is to better under…