Brain-Training trial aims to turn down the ringing
NCT ID NCT07830069
First seen Sep 21, 2026 · Last updated Sep 21, 2026
Summary
Researchers at the University of Zurich are testing whether neurofeedback can ease chronic tinnitus, the persistent ringing or buzzing that affects hearing and quality of life. The study enrolls 24 adults with moderate to severe tinnitus for about nine months. Participants attend 20 neurofeedback sessions and 5 assessments, receiving both real and placebo feedback in a randomized crossover design. The goal is to measure changes in tinnitus loudness and distress, and to see how those changes relate to brain activity.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- individualized EEG neurofeedback, a non-invasive brain-training technique
- What this could lead to
- If it works, neurofeedback could offer a drug-free way to turn down tinnitus loudness and the distress it causes. It could also give researchers a clearer map of the brain activity behind tinnitus.
- What could go wrong
- This is a small, early study of 24 people, and the specific neurofeedback method is new and untested. Placebo-controlled trials of brain training often show modest or short-lived effects, and results in this group may not apply to everyone with tinnitus.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 24 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jan 2027
An estimate. Start dates often move.
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Healthy female or male or diverse patients 18 years to 65 years of age * Persistent chronic, subjective tinnitus with duration of more than 3 months * Signed informed consent after being informed about the study * Fluent in German * Tinnitus with a THI Grade 2 to 4 (18-76 points), moderate to severe * Willing and able to attend all study visits Exclusion Criteria: * Hyperacusis * Concurrent neurological or psychiatric disorders * Regular intake of medication influencing the central nervous system (e.g. neuroleptics, hypnotics, sedatives, and anti-epileptics) * Somatic tinnitus * Asymmetrical hearing (more than 20dB side difference), pantonal hearing loss \> 40dB in any measured frequency up to 2kHz * Women who are pregnant and/or breast feeding * Intention to become pregnant during the course of the study * Known or suspected drug or alcohol abuse * Participation in another study with investigational drug within the 30 days preceding and during the present study, * Enrolment of the investigator, his/her family members, employees and other dependent persons
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
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Other studies related to the condition(s) this trial covers.
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