Tibia fracture
MONDO:0005320Traumatic or pathological injury to the tibia in which the continuity of the bone is broken.
Also known as: bone fracture of tibia, tibia bone fracture
189 clinical trials for this condition and its sub-types, 82 tagged with Tibia fracture itself.
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New knee device tracked in 757-Patient study
Disease control OngoingThis study follows 757 people who received the Persona Partial Knee system, a device used to replace only the damaged part of the knee. The goal is to see how long the implant lasts and how well patients function afterward. Participants have knee arthritis or related conditions a…
Sponsor: Zimmer Biomet • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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Nerve block could ease pain after leg fracture surgery without hiding danger signs
Symptom relief CancelledThis study tests whether a saphenous nerve block can safely reduce pain after surgery for a tibial plateau fracture. Typically, nerve blocks are avoided in these fractures because numbness might mask compartment syndrome, a serious complication. The saphenous nerve block targets …
Sponsor: Stanford University • Aim: Symptom relief
Last updated Jul 03, 2026 00:00 UTC
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New injection aims to ease pain after broken knee surgery
Symptom relief OngoingThis study looks at whether a special pain injection given around the knee during surgery can lower pain for people with a tibial plateau fracture (a break in the top of the shinbone). About 150 adults with this type of fracture will receive the injection, and their pain scores w…
Early phase 1 • Sponsor: University of Utah • Aim: Symptom relief
Last updated Jun 27, 2026 12:24 UTC
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Ear acupuncture aimed at cutting opioid use after broken leg surgery – but trial never started
Symptom relief CancelledThis study planned to test whether adding ear acupuncture to standard pain management could reduce opioid use after surgery for lower leg fractures. It was designed for adults aged 18–64 undergoing ankle or foot fracture repair. However, the trial was withdrawn before enrolling a…
Sponsor: Baylor College of Medicine • Aim: Symptom relief
Last updated Jun 27, 2026 09:09 UTC
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Can moving sooner after knee fracture surgery speed up recovery?
Symptom relief By invitation onlyThis study looks at whether starting weight bearing and active knee exercises soon after surgery for a tibial plateau fracture (a type of knee break) helps reduce pain, improve knee movement, and support bone healing. About 28 adults aged 18 to 50 who had a specific type of fract…
Sponsor: Cairo University • Aim: Symptom relief
Last updated Jun 27, 2026 08:00 UTC
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Withdrawn study: can a cuff boost recovery after leg fracture surgery?
Symptom relief CancelledThis study aimed to see if adding blood flow restriction (BFR) therapy to standard physical therapy improves recovery after surgery for a tibial plateau fracture. It planned to enroll adults who had that surgery and measure knee function, muscle size, and movement over one year. …
Sponsor: Medical College of Wisconsin • Aim: Symptom relief
Last updated Jun 27, 2026 07:56 UTC
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Can ultrasound predict knee pain after broken leg surgery?
Knowledge-focused OngoingThis study follows 50 adults who had surgery for a broken shinbone to see if changes in the kneecap tendon's stiffness relate to knee pain. Researchers use a special ultrasound before and up to 6 months after surgery. The goal is to better understand why some people develop front…
Sponsor: Bagcilar Training and Research Hospital • Aim: Knowledge-focused
Last updated Aug 28, 2026 00:00 UTC
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Can walking sooner after a broken knee speed up recovery? new study aims to find out.
Knowledge-focused By invitation onlyThis study compares two recovery plans for people who had surgery for a specific type of knee fracture (unicondylar tibial plateau fracture). One group will start putting weight on their leg after 6 weeks, while the other follows the standard 10-week wait. Researchers will measur…
Sponsor: University of Utah • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:25 UTC
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Knee fracture inflammation linked to arthritis risk
Knowledge-focused OngoingThis study looks at how the body's inflammatory response after a specific type of knee fracture might be linked to developing arthritis later. Researchers will measure inflammatory markers in the joint fluid and blood of 60 adults with a tibial plateau fracture. They will also us…
Sponsor: University of Utah • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:25 UTC
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Gene study aims to unlock why some leg fractures lead to dangerous muscle swelling
Knowledge-focused By invitation onlyThis study compares genetic differences and muscle gene activity in people who develop acute compartment syndrome after a leg fracture versus those who do not. Researchers will measure a protein called myostatin in muscle tissue. The goal is to better understand why some people g…
Sponsor: University of Utah • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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Stitches or staples? small study aims to settle the debate for leg fracture surgery
Knowledge-focused OngoingThis pilot study tests whether stitches or staples are better for closing surgical wounds after fixing broken leg bones. About 50 adults with certain leg fractures will be randomly assigned to one closure method. The main goal is to see if such a study is practical, not to prove …
Sponsor: University of Southern California • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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1500 fracture patients tracked to unlock recovery secrets
Knowledge-focused OngoingThis study follows about 1500 adults with hip, shin, ankle, upper arm, or wrist fractures for up to one year. Researchers collect information on healing, patient-reported symptoms, and activity patterns using questionnaires and wearable sensors. The goal is to understand recovery…
Sponsor: AO Innovation Translation Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:10 UTC
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Joint Decision-Making: what do patients really want?
Knowledge-focused By invitation onlyThis study asks over 2,300 people with various joint conditions (like arthritis, fractures, and hip problems) to fill out surveys about their treatment preferences. Researchers want to learn how factors like pain, recovery time, cost, and surgery versus non-surgery affect patient…
Sponsor: Duke University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
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Walk now or wait? new study tests early weightbearing after fracture surgery
Knowledge-focused By invitation onlyThis study looks at whether patients with surgically treated leg, pelvis, or hip socket fractures can safely start walking right away instead of waiting 6-12 weeks. About 100 adults will be randomly assigned to immediate weightbearing or delayed weightbearing. The goal is to see …
Sponsor: University of Maryland, Baltimore • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:15 UTC
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Ankle brace study pulled before it even started
Knowledge-focused CancelledThis study aimed to see if custom carbon fiber braces could reduce forces on the ankle joint after a fracture, potentially lowering the risk of arthritis. It planned to enroll adults with healed ankle fractures and test different brace designs. However, the study was withdrawn be…
Sponsor: University of Iowa • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC
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Massive study follows 1,000 kids with fractures to find best treatments
Knowledge-focused OngoingThis registry follows 1,000 children with long bone fractures to see how different treatments (casts, surgery, or splints) affect healing. Doctors collect data on recovery, movement, and complications over two years. The goal is to learn which treatments work best for different f…
Sponsor: AO Innovation Translation Center • Aim: Knowledge-focused
Last updated Jun 26, 2026 16:33 UTC