Withdrawn study: can a cuff boost recovery after leg fracture surgery?
NCT ID NCT06589115
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study aimed to see if adding blood flow restriction (BFR) therapy to standard physical therapy improves recovery after surgery for a tibial plateau fracture. It planned to enroll adults who had that surgery and measure knee function, muscle size, and movement over one year. However, the trial was withdrawn before any participants were enrolled, so no data were collected.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Blood Flow Restriction Cuff
- What this could lead to
- If it had worked, this could point toward a way to speed up recovery and reduce muscle loss after leg fracture surgery.
- What could go wrong
- The trial was withdrawn before enrolling anyone, so no results are available. It is unclear if the approach is effective or safe.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Expected to start
-
Dec 2025
An estimate. Start dates often move.
- Expected to finish
-
Dec 2028
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 years and older
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Equal to or greater than 18 years of age 2. ORIF (open reduction and internal fixation) of a closed unicondylar tibial plateau fracture 3. Planning to attend physical therapy at one of the eligible Froedtert locations with BFR therapy capabilities Exclusion Criteria: 1. Patient is unable to provide consent 2. At time of tibial plateau fracture has evidence of a(n) 1. Open fracture(s) 2. Fracture(s) with associated vascular injury, 3. Fracture(s) with extensive soft tissue injury preventing the ability to apply a tourniquet 4. Ipsilateral or contralateral lower extremity fracture(s) 5. Pelvic or spinal trauma 3. History of deep venous thrombosis (DVT) 4. History of peripheral vascular disease 5. Body Mass Index \> 40 6. Any history of condition that would affect the patient's ability to bear weight as tolerated post-operatively.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Tibial plateau fractures are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Medical College of Wisconsin
Milwaukee, Wisconsin, 53226, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.