Stomatitis

Researchers are studying whether aloe vera mouthwash can prevent or reduce the severity of oral mucositis, a painful mouth sore that often affects people receiving chemotherapy for acute leukemia. The trial compares aloe vera mouthwash plus usual care against usual care alone in …

Children who receive hematopoietic stem cell transplants often develop painful mouth sores called oral mucositis, which can lead to poor eating, infection, and longer hospital stays. This trial tests whether a structured oral care program, including caregiver education, supervise…

This study tests whether light therapy (photobiomodulation) can prevent mouth sores in children receiving chemotherapy. Fifty children aged 0-30 will receive daily light treatments during hospital stays and at home. Researchers will check if the therapy is easy to use and accepta…

This pilot study tests two light therapy devices—one placed inside the mouth and one outside—to prevent and treat painful mouth sores caused by radiation therapy. Sixty adults with oral cavity or oropharynx cancer will receive light sessions twice a week for prevention, then thre…

This study tests whether a modified herbal mouthwash can prevent painful mouth sores caused by radiation therapy in people with head and neck cancer. About 156 participants will use either the herbal mouthwash or a placebo during their radiation treatment. The goal is to see if t…

This study tests if a special light (photobiomodulation) can prevent and treat painful mouth sores caused by chemotherapy in children aged 4-17 with cancer. Half of the 49 participants will get light therapy, and the other half will get a standard gel. The goal is to see if the l…

This study tests an oral spray made from stem cell exosomes to prevent severe mouth sores in head and neck cancer patients undergoing radiation. 200 participants will use the spray three times daily, starting a week before radiation and continuing for two weeks after. The goal is…

This study tests two simple, low-cost methods—cold application (like ice chips) and artificial saliva—to prevent painful mouth sores caused by chemotherapy. About 60 cancer patients starting chemo will be randomly assigned to one of the two treatments or standard care. The goal i…

Researchers are testing a gel made from orange peel extract to see if it can reduce the severity of mouth sores caused by radiation therapy in people with head and neck cancer. Thirty adults receiving radiation will be split into two groups: one gets the orange peel gel, the othe…

This trial compares two simple treatments—sucking on ice chips or using a lidocaine spray—to see which better prevents or reduces painful mouth sores caused by chemotherapy. About 60 adults with cancer who are about to receive chemotherapy will be randomly assigned to one of the …

This study tests whether a traditional Chinese herbal drink called Sancai Fengsui Decoction can help heal painful mouth sores caused by radiation therapy for head and neck cancer. About 126 adults who have developed moderate to severe mouth sores after radiation will receive eith…

This study tests whether sucking on ice chips during chemotherapy can prevent or reduce the severity of painful mouth sores (oral mucositis) in cancer patients. 102 adults receiving 5-fluorouracil or methotrexate will be randomly assigned to either get ice chips during infusion p…

This study tests a painless light treatment called photobiomodulation for children aged 3 to 14 who get severe mouth sores from chemotherapy. The treatment uses a handheld red light device for about 5-10 minutes daily for four days, alongside standard care. Researchers want to se…

This phase 2 trial tests whether taking taurine (a common amino acid) can prevent or reduce severe mouth sores caused by radiation therapy in people with nasopharyngeal cancer. 130 patients will take taurine pills or receive standard care starting 3 days before radiation until 1 …

This study tests whether daily red light therapy can prevent or reduce skin and mouth side effects in children aged 0-16 receiving radiation for cancer. About 248 kids will get a daily LED light treatment on the radiated area. Researchers will compare their side effects to those …

This study tests whether a mobile education app based on Kolcaba's Comfort Theory can improve comfort and well-being for people living with a stoma. About 68 adults scheduled for stoma surgery will be randomly assigned to use the app plus standard care, or standard care alone. Th…

This study will test whether rinsing with cold water (15-20°C) reduces mouth soreness and improves comfort compared to room-temperature water in 200 head and neck cancer patients undergoing radiotherapy. Participants will rinse four times daily for six weeks. The goal is to see i…

This study looks at whether music therapy can reduce painful mouth sores (oral mucositis) in children with cancer. Researchers will interview 50 families online to learn about their experiences with music therapy. The goal is to find patterns that could lead to better, drug-free …

This study looks back at the medical records of 60 adults with head and neck cancer who received radiation therapy, with or without chemotherapy, and used a topical mouth rinse made from olive oil, betaine, and xylitol. The goal is to see how often severe mouth sores (oral mucosi…

This study tests a new approach called 'Flipped Discharge' for people with colorectal cancer who have a stoma after surgery. Instead of focusing care in the hospital, it shifts support to the home, with a nurse visit or video follow-up three days after discharge. The goal is to s…

This study looks at whether playing an escape room game helps nursing students learn more about stoma care and feel more confident. About 60 students will be split into two groups: one will get a lecture plus the escape room game, and the other will get only a traditional lecture…