Scoliosis
MONDO:0005392A congenital or acquired spinal deformity characterized by lateral curvature of the spine.
234 clinical trials for this condition and its sub-types, 137 tagged with Scoliosis itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Scoliosis
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Idiopathic scoliosis 66 trials · 181 incl. sub-types
2 sub-types
- Adolescent idiopathic scoliosis 137 trials
- Juvenile idiopathic scoliosis 9 trials
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Can simple yoga poses straighten curved spines in children?
Disease control OngoingResearchers are testing whether a short daily routine of one or two yoga poses can reduce spinal curvature in children aged 8 to 12 with juvenile idiopathic lumbar scoliosis. Participants practice the poses for 5 to 7 minutes, three times a day, for four months. Some children sta…
Sponsor: Manhattan Physical Medicine and Rehabilitation, LLP • Aim: Disease control
Last updated Sep 16, 2026 00:00 UTC
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Can augmented reality make spinal screws safer?
Disease control OngoingThis trial compares two computer-assisted navigation methods with the traditional free-hand technique for placing pedicle screws during spinal deformity surgery. The goal is to see which approach places screws most accurately, using a CT scan during the operation to check. The st…
Sponsor: Karolinska Institutet • Aim: Disease control
Last updated Aug 29, 2026 00:00 UTC
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Could pelvic floor training straighten scoliosis curves?
Disease control OngoingThis trial tests whether adding pelvic floor muscle training to standard scoliosis-specific exercises can better reduce spine curvature in adolescents with idiopathic scoliosis. Participants aged 10-18 with mild to moderate curves will be randomly assigned to either exercises alo…
Sponsor: Gazi University • Aim: Disease control
Last updated Aug 06, 2026 00:00 UTC
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New tethering technique may offer Motion-Sparing alternative to spinal fusion for kids with scoliosis
Disease control By invitation onlyThis study tests a device called the Zimmer Biomet Tether System, which is surgically placed along the spine to correct curvature in children with scoliosis. Unlike traditional spinal fusion, which permanently joins vertebrae, this tethering approach aims to guide growth while pr…
Sponsor: Mayo Clinic • Aim: Disease control
Last updated Jul 09, 2026 00:00 UTC
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New minimally invasive surgery could ease recovery for kids with spine curvature
Disease control OngoingThis study compares a new, less invasive surgery to the standard open surgery for children with paralytic scoliosis (a curved spine) after a spinal cord injury. The minimally invasive approach uses smaller cuts and aims to correct the spine while causing less blood loss, fewer co…
Sponsor: The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School • Aim: Disease control
Last updated Jun 27, 2026 12:36 UTC
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AI app takes on scoliosis: could your phone replace physical therapy?
Disease control OngoingThis study tests whether a smartphone app that uses artificial intelligence can help teens with scoliosis do better exercises than traditional physical therapy. The app analyzes posture and creates a personalized workout plan. Researchers will compare spine curve changes and how …
Sponsor: Jinan University Guangzhou • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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New spine device aims to fix crooked necks
Disease control OngoingThis study is testing a new surgical system called Symphony for adults with severe neck deformities. About 100 patients will receive the device to straighten the spine and relieve pain. Researchers will track pain, disability, and complications for up to two years.
Sponsor: International Spine Study Group Foundation • Aim: Disease control
Last updated Jun 27, 2026 09:05 UTC
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New spine surgery aims to straighten scoliosis in teens
Disease control OngoingThis study tests a spine surgery for 20 teenagers (ages 12-21) with a specific type of scoliosis called Lenke 1. The goal is to correct the spine curve and improve quality of life. Researchers will measure how well the surgery works using X-rays and patient questionnaires.
Sponsor: Istituto Ortopedico Rizzoli • Aim: Disease control
Last updated Jun 27, 2026 08:07 UTC
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Spine implant safety under the microscope: 1,050 patients enrolled
Disease control By invitation onlyThis study is tracking 1,050 adults who are getting NuVasive interbody implants during spine surgery for conditions like degenerative disc disease or spinal stenosis. Researchers are monitoring complications, bone fusion, and patient-reported pain relief over 24 months. The goal …
Sponsor: NuVasive • Aim: Disease control
Last updated Jun 27, 2026 08:06 UTC
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New study tests drug-free pain relief after back surgery to cut opioid use
Symptom relief OngoingThis study looks at two different ways to manage pain after lower back surgery without relying on drugs. About 267 adults will be randomly assigned to either standard care or an enriched pain management plan. The goal is to see which approach better reduces pain and helps people …
Sponsor: Dan Rhon • Aim: Symptom relief
Last updated Jun 27, 2026 12:38 UTC
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Video games vs. standard rehab: a new hope for scoliosis recovery?
Symptom relief By invitation onlyThis study looks at whether playing active video games can help teenagers regain balance and posture better than standard exercises after scoliosis surgery. About 51 teens who had spinal fusion will be split into three groups: video game training, standard stabilization exercises…
Sponsor: Istanbul University - Cerrahpasa • Aim: Symptom relief
Last updated Jun 27, 2026 12:34 UTC
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New combo aims to ease Post-Surgery pain without strong opioids
Symptom relief OngoingThis study tests whether combining different doses of esketamine and dexmedetomidine can improve pain relief after scoliosis correction surgery. About 312 adults will receive one of several drug combinations alongside standard painkillers. The goal is to reduce pain and the need …
Phase 4 • Sponsor: Peking University First Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:06 UTC
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Stretching before surgery: could simple exercises improve scoliosis outcomes?
Symptom relief By invitation onlyThis study tests whether doing special flexibility exercises for 6 months before spinal fusion surgery helps teens with scoliosis. Researchers want to see if it leads to fusing fewer vertebrae, better curve correction, shorter surgery, and less time in the hospital. Forty teens a…
Sponsor: Eric Parent • Aim: Symptom relief
Last updated Jun 27, 2026 12:05 UTC
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Kids' scoliosis study tracks movement and muscle changes
Knowledge-focused By invitation onlyThis study follows 200 children aged 9-16 with scoliosis to see how spinal fusion surgery or bracing affects their muscle function and daily activity. Participants wear activity monitors and undergo muscle stiffness tests at the start and one year later. The goal is to learn more…
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Sep 20, 2026 00:00 UTC
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Can 3D-printed guides tame the toughest spine screws?
Knowledge-focused OngoingResearchers are reviewing past spinal fusion surgeries to see if patient-specific guides, called MySpine, place screws safely even in the most challenging bone. They will compare nerve irritation rates between standard screws and those in anatomically complex positions, known as …
Sponsor: I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio • Aim: Knowledge-focused
Last updated Aug 29, 2026 00:00 UTC
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Scoliosis's hidden toll: can we predict lung and heart risks?
Knowledge-focused OngoingThis study looks back at 10 years of medical records from a scoliosis referral center to see how frequently adults with scoliosis who had surgery also develop restrictive breathing problems or signs of pulmonary hypertension on echocardiography. By analyzing data from 174 patient…
Sponsor: Poitiers University Hospital • Aim: Knowledge-focused
Last updated Aug 14, 2026 00:00 UTC
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Could a Lying-Down scan replace standing X-Rays for scoliosis?
Knowledge-focused OngoingThis study tests whether a special type of X-ray called DXA, taken while lying down, can measure spine curves as well as standard standing X-rays in people with scoliosis. About 20 participants will have both types of images taken, and researchers will compare the results and ask…
Sponsor: Sheffield Children's NHS Foundation Trust • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:09 UTC
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Spine curve study: surgery vs. no surgery – which works better?
Knowledge-focused OngoingThis study follows nearly 2,000 adults with spinal deformity (curved spine) to compare outcomes between those who have surgery and those who do not. Researchers track X-rays, pain levels, and quality of life over time. The goal is to learn which approach leads to better long-term…
Sponsor: International Spine Study Group Foundation • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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Could sleep problems worsen scoliosis in kids? new study investigates
Knowledge-focused OngoingThis study looks at whether sleep-disordered breathing, like obstructive sleep apnea, is linked to worsening spine curves in children with idiopathic scoliosis. Researchers will follow 405 children aged 6 to 15 with mild to moderate scoliosis. They will measure spine curves and s…
Sponsor: Second Affiliated Hospital of Wenzhou Medical University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC
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Spine surgery fluid study pulled before starting
Knowledge-focused CancelledThis study was designed to see if a special saltwater solution (buffered 2% hypertonic saline) is better than standard fluids for children and teens having spine surgery for scoliosis. The goal was to compare how the body's acid-base balance and electrolyte levels changed during …
Phase 2/3 • Sponsor: Joseph D. Tobias • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC
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Brain oxygen check: new study monitors teens during spine surgery
Knowledge-focused By invitation onlyThis study looks at how moving a patient's body position during scoliosis surgery changes oxygen levels in the brain. Researchers will use a non-invasive light device on 50 teens aged 10-21. The goal is to learn how different head elevations affect brain oxygenation, which could …
Sponsor: Joseph D. Tobias • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:55 UTC
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Teens' genes may predict pain after back surgery
Knowledge-focused OngoingThis study looks at how a child's genes and emotions influence pain after major spine surgery. Researchers will follow 880 teens aged 10-18 having spine fusion for scoliosis or similar conditions. They will measure pain levels, breathing problems, and nausea after surgery, and ch…
Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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Standing on a mat could reveal clues about scoliosis
Knowledge-focused OngoingThis study looks at 84 teens with scoliosis to see if the way they put pressure on their feet is linked to the shape of their spine curve. Participants simply stand on a pressure-sensing mat while doctors also check their spine X-rays. The goal is to better understand how scolios…
Sponsor: Mahmoud Ibrahim Elsayed Aly Mahmoud • Aim: Knowledge-focused
Last updated Jun 26, 2026 16:59 UTC