New minimally invasive surgery could ease recovery for kids with spine curvature
NCT ID NCT07594574
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares a new, less invasive surgery to the standard open surgery for children with paralytic scoliosis (a curved spine) after a spinal cord injury. The minimally invasive approach uses smaller cuts and aims to correct the spine while causing less blood loss, fewer complications, and shorter hospital stays. The trial includes 39 children aged 6 to 20 with severe pelvic tilt and spine curvature.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Posterior minimally invasive correction surgery
- What this could lead to
- If successful, this could offer a safer, less traumatic surgical option for children with paralytic scoliosis, reducing hospital stays and complications.
- What could go wrong
- This is a small, early-stage trial with only 39 participants, so results may not apply to all children. Surgery always carries risks like infection or implant issues.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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39 people
The number who actually took part.
- Started
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Aug 2024
- Expected to finish
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Sep 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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6 to 20 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age 6 to 20 years at the time of enrollment. * Diagnosis of paralytic scoliosis secondary to spinal cord injury during childhood. * Severe pelvic obliquity, defined as pelvic obliquity angle greater than 15 degrees on sitting full-spine anteroposterior radiographs. * Major coronal scoliosis curve with Cobb angle greater than 40 degrees, or progressive deformity considered to require surgical correction by the treating spine deformity team. * Nonambulatory status or severe lower-limb motor dysfunction after spinal cord injury. * Planned surgical correction requiring spinopelvic fixation. * Ability to undergo sitting full-spine radiographic assessment before surgery and during follow-up. * Written informed consent provided by the parent or legal guardian, with participant assent when applicable. Exclusion Criteria: * Idiopathic scoliosis, congenital scoliosis, syndromic scoliosis, or spinal deformity caused by etiologies other than spinal cord injury. * Neuromuscular scoliosis caused by cerebral palsy, spinal muscular atrophy, muscular dystrophy, myelomeningocele, poliomyelitis, or other primary neuromuscular diseases. * Previous spinal deformity correction surgery or previous long-segment spinal fusion. * Active systemic infection or uncontrolled local infection at the planned surgical site. * Severe pressure ulcer, osteomyelitis, or soft tissue condition that precludes safe posterior spinal surgery. * Severe cardiopulmonary, hematologic, hepatic, renal, or other systemic disease that makes the participant unsuitable for major spinal surgery. * Coagulation disorder or other condition associated with unacceptable bleeding risk. * Inability to complete the planned follow-up schedule. * Participation in another interventional trial that may affect the outcomes of this study.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Drum Tower Hospital of Nanjing University Medical School
Nanjing, Jiangsu, 210000, China
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