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New combo aims to ease Post-Surgery pain without strong opioids

NCT ID NCT06062550

First seen Apr 16, 2026 · Last updated Jun 19, 2026 · Updated 11 times

Summary

This study tests whether combining different doses of esketamine and dexmedetomidine can improve pain relief after scoliosis correction surgery. About 312 adults will receive one of several drug combinations alongside standard painkillers. The goal is to reduce pain and the need for strong opioids, which can cause side effects and tolerance.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Beijing University First Hospital

    Beijing, Beijing Municipality, 100034, China

Conditions

The condition(s) this trial relates to.

Pain, Postoperative scoliosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.