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Spine curve study: surgery vs. no surgery – which works better?

NCT ID NCT00738439

Knowledge-focused Sponsor: International Spine Study Group Foundation Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study follows nearly 2,000 adults with spinal deformity (curved spine) to compare outcomes between those who have surgery and those who do not. Researchers track X-rays, pain levels, and quality of life over time. The goal is to learn which approach leads to better long-term results.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

1,999 people

The number who actually took part.

Start date

Oct 2008

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients greater than 18 years of age who meet inclusion criteria.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Diagnosis of adult degenerative or idiopathic scoliosis with a curvature of the spine measuring greater than or equal to 20 degrees * Sagittal Vertical Axis (SVA) \> 5cm * Pelvic Tilt \> 25 degrees * Thoracic kyphosis \> 60 degrees * Age 18 or greater at the time of enrollment. Exclusion Criteria: * Diagnosis of scoliosis other than degenerative or idiopathic (i.e. paralytic/neuromuscular, congenital) * Age \<18 yrs at time of surgery or initial consultation

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Conditions

The condition(s) this trial relates to.

idiopathic scoliosis Kyphosis scoliosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Spinal deformity

Contacts and locations

Locations

  • Denver International Spine Center

    Denver, Colorado, 80218, United States

  • Doug Burton, MD

    Kansas City, Kansas, 66160-7387, United States

  • Hospital for Special Surgery

    New York, New York, 10021, United States

  • Johns Hopkins University

    Baltimore, Maryland, 21287-0882, United States

  • NYU Hospital for Joint Diseases

    New York, New York, 10010, United States

  • Scripps Clinic

    La Jolla, California, 92037, United States

  • University of California - Davis

    Sacramento, California, 95817, United States

  • University of California - San Francisco Medical Center

    San Francisco, California, 94143, United States

  • University of Virginia

    Charlottesville, Virginia, 22908, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.