Schizophrenia 1
MONDO:0008414A schizophrenia that has material basis in an autosomal dominant mutation of SCZD1 on chromosome 5q23-q35.
Also known as: SCZD1, schizophrenia 1, schizophrenia 1 with or without an affective disorder, schizophrenia susceptibility locus, chromosome 5-related
96 clinical trials for this condition and its sub-types, 28 tagged with Schizophrenia 1 itself.
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Generic cariprazine put to the test: will it match the brand?
Disease control CompletedThis trial compares a generic form of cariprazine (a drug used for schizophrenia) to the brand-name version Reagila®. Healthy adults aged 18 to 55 receive a single dose of either the generic or brand drug under fasting conditions. The main goal is to see if the generic version is…
Phase 1 • Sponsor: Humanis Saglık Anonim Sirketi • Aim: Disease control
Last updated Jul 10, 2026 00:00 UTC
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Gut bacteria may tame antipsychotic side effects in schizophrenia
Disease control CompletedThis study tested whether a probiotic supplement (Pediococcus acidilactici) could reduce metabolic problems like high cholesterol and blood sugar caused by antipsychotic drugs. 36 adults with first-episode psychosis or schizophrenia took the probiotic or a placebo alongside their…
Sponsor: Manuel Jesús Cuesta Zurita • Aim: Disease control
Last updated Jun 27, 2026 12:07 UTC
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Virtual reality could boost brain power in schizophrenia
Symptom relief CompletedThis study tests whether immersive virtual reality (VR) can safely help people with schizophrenia improve their thinking skills, reduce symptoms, and function better in daily life. Forty adults with schizophrenia or schizoaffective disorder will either receive VR-based cognitive …
Sponsor: Azienda Sanitaria Locale Napoli 3 Sud, UOCSM Torre del Greco • Aim: Symptom relief
Last updated Jun 27, 2026 14:00 UTC
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New schizophrenia drug shows promise in reducing symptoms
Symptom relief CompletedThis study tested a new medication called HS-10380 in 363 Chinese adults hospitalized with acute schizophrenia. The goal was to see if it reduces symptoms like hallucinations and delusions better than a placebo or an existing drug. Participants took the drug for 6 weeks, and doct…
Phase 2 • Sponsor: Jiangsu Hansoh Pharmaceutical Co., Ltd. • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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Can sharing memories help schizophrenia patients think and connect better?
Symptom relief CompletedThis study tested whether a group reminiscence program—where people share and discuss past memories—is practical and helpful for adults hospitalized with schizophrenia. Thirty-eight participants took part in an 8-week program. Researchers measured changes in thinking, communicati…
Sponsor: The Hashemite University • Aim: Symptom relief
Last updated Jun 27, 2026 12:04 UTC
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Yoga and mindfulness show promise for happiness in schizophrenia
Symptom relief CompletedThis study looked at whether a 6-week mindfulness-based yoga program could improve psychological well-being and happiness in adults with schizophrenia. 91 participants from community mental health centers were randomly assigned to either the yoga program or their usual care. The …
Sponsor: Tarsus University • Aim: Symptom relief
Last updated Jun 27, 2026 12:00 UTC
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Can a gentle brain zap ease multiple mental health conditions?
Symptom relief CompletedThis study tested whether a gentle electrical current applied to the scalp (tDCS) can reduce symptoms of major depression, schizophrenia, OCD, generalized anxiety, and insomnia. 320 adults aged 16–65 received multiple sessions over weeks. Researchers measured symptom changes usin…
Sponsor: Menoufia University • Aim: Symptom relief
Last updated Jun 27, 2026 09:10 UTC
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Role-Play with a simulated patient: a new way to train nurses in mental health?
Knowledge-focused CompletedThis study asks whether a scenario-based simulation, where nursing students interact with an actor portraying a person with schizophrenia, can boost their knowledge, empathy, and caregiving skills. Around 105 students will complete questionnaires before and after the simulation, …
Sponsor: Medipol University • Aim: Knowledge-focused
Last updated Aug 13, 2026 00:00 UTC
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Zapping the brain to understand schizophrenia: small study tests TMS on attention and cravings
Knowledge-focused CompletedThis completed study tested whether targeted brain stimulation (TMS) could affect attention and nicotine cravings in 15 people with schizophrenia or schizoaffective disorder who smoke. Researchers applied different types of TMS to a brain network linked to attention and measured …
Sponsor: Beth Israel Deaconess Medical Center • Aim: Knowledge-focused
Last updated Aug 01, 2026 00:00 UTC