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Pterygium
MONDO:0005085A wedge-shaped fibrovascular lesion arising from the bulbar conjunctiva and extending to the cornea. It is caused by chronic exposure to solar ultraviolet radiation, heat, and dust. It may cause severe vision loss. Studies have linked pterygium to neoplastic proliferation and suggest that it may be a stem cell disorder.
Also known as: pterygium of conjunctiva and cornea
1469 clinical trials for this condition and its sub-types, 16 tagged with Pterygium itself.
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Sub-types of Pterygium
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Conjunctival pterygium 5 trials
1 sub-type
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Double pterygium 0 trials
Most studied deeper sub-types
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Which eye surgery better restores clear vision after pterygium?
Disease control CompletedThis trial compares two surgical techniques for removing a pterygium, a fleshy growth on the eye's surface that can distort vision. Researchers are testing whether using a piece of the patient's own conjunctiva (the clear tissue covering the eye) or a preserved amniotic membrane …
Sponsor: Instituto de Oftalmología Fundación Conde de Valenciana • Aim: Disease control
Last updated Aug 19, 2026 00:00 UTC
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Lab-grown stem cells may restore damaged eye surfaces
Disease control CompletedThis study tests whether a graft made from a patient's own or donor stem cells can repair the cornea's surface in people with limbal stem cell deficiency, a condition that causes pain, scarring, and vision loss. A small biopsy of limbal tissue is taken from a healthy eye or donor…
Sponsor: Veerle Van Gerwen • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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New eye drops aim to tame pterygium redness
Disease control CompletedThis study tested an eye drop called RMP-A03 in 77 healthy volunteers and people with pterygium, a fleshy growth on the eye. The goal was to see if it safely reduces redness and controls the condition. Participants received either a low dose, high dose, or placebo drops, and rese…
Phase 2 • Sponsor: Suzhou Raymon Pharmaceuticals Company, Ltd. • Aim: Disease control
Last updated Jun 27, 2026 13:03 UTC
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Eye gel may replace painful needle in pterygium surgery
Symptom relief CompletedThis study tested whether a numbing gel (lidocaine) works as well as a needle injection for pain relief during pterygium surgery. 41 adults having pterygium removal took part. The goal was to see if the gel causes less pain and eye dryness after surgery.
Phase 4 • Sponsor: Vrije Universiteit Brussel • Aim: Symptom relief
Last updated Aug 27, 2026 00:00 UTC
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Surgeons try apple vision pro during cataract operations
Knowledge-focused CompletedThis study tested whether surgeons can safely use an Apple Vision Pro headset to view a microscope during cataract and other eye surgeries. 45 adults having elective eye surgery took part. The goal was to see if the headset is safe and comfortable for the surgeon, not to change h…
Sponsor: Sharp HealthCare • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:03 UTC
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New digital tool could make eye scar assessment more accurate
Knowledge-focused CompletedThis study tested a digital color scale to objectively measure scarring of the eye's surface in people with recurrent pterygium, a growth that can come back after surgery. Researchers took photos of 25 patients' eyes and used software to analyze the scar tissue. The goal was to s…
Sponsor: Instituto de Oftalmología Fundación Conde de Valenciana • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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Can a single nurse monitor multiple eye surgeries safely?
Knowledge-focused CompletedThis study looked at whether a central monitoring station outside the operating room could safely replace having an anesthesia nurse in each room during eye surgeries like cataract removal. Researchers compared the rate of complications (like high blood pressure or low oxygen) be…
Sponsor: Fondation Ophtalmologique Adolphe de Rothschild • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC
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No-Stitch eye surgery shows promise for pterygium patients
Knowledge-focused CompletedThis study looked at two methods for fixing a tissue graft after removing a pterygium, a growth on the eye's surface. In 30 patients with pterygium in both eyes, one eye received stitches and the other did not. Researchers used special imaging to compare healing, comfort, and gra…
Sponsor: Minia University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC