No-Stitch eye surgery shows promise for pterygium patients
NCT ID NCT07307820
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at two methods for fixing a tissue graft after removing a pterygium, a growth on the eye's surface. In 30 patients with pterygium in both eyes, one eye received stitches and the other did not. Researchers used special imaging to compare healing, comfort, and graft stability over one month. The goal was to see if the no-stitch method works as well or better than stitches.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could show that a sutureless method for pterygium surgery is just as effective as suturing, potentially reducing patient discomfort and surgery time.
- What could go wrong
- This is a small, completed study with only 30 patients, so results may not apply to everyone. The sutureless technique might still carry risks like graft slippage.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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30 people
The number who actually took part.
- Started
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Sep 2025
- Finished
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Dec 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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Up to 60 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria Age 18 to 65 years (both sexes). Diagnosis of bilateral primary nasal pterygium requiring surgical excision (both eyes affected). Horizontal corneal encroachment of the pterygium ≥ 2.0 mm in each eye. Lesions amenable to conjunctival autograft coverage with expected graft size obtainable from superior bulbar conjunctiva. Willingness and ability to attend scheduled follow-up visits for 1 month postoperatively. Able to provide written informed consent. Exclusion Criteria Recurrent pterygium in either eye. Previous ocular surgery on the study eye(s) (including prior pterygium surgery) or conjunctival grafting. Active ocular surface disease or infection (e.g., conjunctivitis, keratitis) at screening. Severe dry eye disease (e.g., Schirmer's test ≤ 5 mm or TBUT \< 5 s) likely to affect healing. Significant ocular comorbidities affecting wound healing or outcome interpretation: uncontrolled glaucoma with conjunctival filtering surgery, ocular surface cicatrizing disorders (e.g., ocular pemphigoid), severe blepharitis, or severe meibomian gland dysfunction. Systemic conditions that impair wound healing or increase surgical risk (e.g., uncontrolled diabetes mellitus with HbA1c \> 8.0%, connective tissue disorders, immunosuppression, chronic systemic corticosteroid use). Current use of anticoagulant therapy that cannot be safely paused per local perioperative protocol (if this precludes safe graft fixation). Pregnancy or breastfeeding. Known allergy to any material used in the procedure or postoperative medications. Inability to comply with follow-up schedule or provide informed consent (e.g., cognitive impairment, planning to move away).
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Minia University Hospital
Minya, Minia Governorate, 61511, Egypt
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Other studies related to the condition(s) this trial covers.